HCSGD entry for PAOX

1. General information

Official gene symbolPAOX
Entrez ID196743
Gene full namepolyamine oxidase (exo-N4-amino)
Other gene symbolsPAO
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005102Receptor bindingIPImolecular_function
GO:0005782Peroxisomal matrixTAScellular_component
GO:0006595Polyamine metabolic processTASbiological_process
GO:0006596Polyamine biosynthetic processTASbiological_process
GO:0006598Polyamine catabolic processIDAbiological_process
GO:0006805Xenobiotic metabolic processTASbiological_process
GO:0009446Putrescine biosynthetic processIDAbiological_process
GO:0009447Putrescine catabolic processIDAbiological_process
GO:0034641Cellular nitrogen compound metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046203Spermidine catabolic processIDAbiological_process
GO:0046208Spermine catabolic processIDAbiological_process
GO:0046592Polyamine oxidase activityIDAmolecular_function
GO:0052899N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activityIEAmolecular_function
GO:0052901Spermine:oxygen oxidoreductase (spermidine-forming) activityIEAmolecular_function
GO:0052902Spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activityIEAmolecular_function
GO:0052903N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activityIEAmolecular_function
GO:0052904N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activityTASmolecular_function
GO:0055114Oxidation-reduction processIDAbiological_process
GO:1901307Positive regulation of spermidine biosynthetic processIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.62587957900.83143149960.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0226089324
GSE13712_SHEARDown-0.0598774776
GSE13712_STATICUp0.0935970714
GSE19018Down-0.0293301606
GSE19899_A1Down-0.0800262950
GSE19899_A2Down-0.0468770733
PubMed_21979375_A1Up0.3120390134
PubMed_21979375_A2Down-0.2258340751
GSE35957Down-0.1465401017
GSE36640Up0.1158699719
GSE54402Up0.1293133434
GSE9593Up0.0147990197
GSE43922Up0.0572161984
GSE24585Up0.2166028222
GSE37065Up0.0399531692
GSE28863_A1Down-0.1323380831
GSE28863_A2Down-0.1030661973
GSE28863_A3Up0.2837973674
GSE28863_A4Up0.1191193352
GSE48662Up0.0739797737

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.