HCSGD entry for EFNB2
1. General information
| Official gene symbol | EFNB2 |
|---|---|
| Entrez ID | 1948 |
| Gene full name | ephrin-B2 |
| Other gene symbols | EPLG5 HTKL Htk-L LERK5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001945 | Lymph vessel development | IEA | biological_process |
| GO:0002042 | Cell migration involved in sprouting angiogenesis | IDA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0007155 | Cell adhesion | IDA | biological_process |
| GO:0007267 | Cell-cell signaling | TAS | biological_process |
| GO:0007399 | Nervous system development | IEA | biological_process |
| GO:0009653 | Anatomical structure morphogenesis | TAS | biological_process |
| GO:0009887 | Organ morphogenesis | IEA | biological_process |
| GO:0010839 | Negative regulation of keratinocyte proliferation | IEA | biological_process |
| GO:0016032 | Viral process | IEA | biological_process |
| GO:0030154 | Cell differentiation | IEA | biological_process |
| GO:0046875 | Ephrin receptor binding | IPI | molecular_function |
| GO:0048013 | Ephrin receptor signaling pathway | IDA | biological_process |
| GO:0050920 | Regulation of chemotaxis | IDA | biological_process |
| GO:2000727 | Positive regulation of cardiac muscle cell differentiation | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8453500779 | 0.0013682611 | 0.9999902473 | 0.0715648221 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1633316148 |
| GSE13712_SHEAR | Down | -2.0159645040 |
| GSE13712_STATIC | Down | -2.2434398904 |
| GSE19018 | Down | -1.0005439476 |
| GSE19899_A1 | Up | 0.0210933882 |
| GSE19899_A2 | Up | 0.1324895198 |
| PubMed_21979375_A1 | Up | 0.2510690597 |
| PubMed_21979375_A2 | Up | 0.4943042887 |
| GSE35957 | Down | -2.2614907379 |
| GSE36640 | Down | -1.3276229793 |
| GSE54402 | Up | 0.5384385221 |
| GSE9593 | Up | 0.7640060236 |
| GSE43922 | Up | 0.0340742001 |
| GSE24585 | Down | -1.1185616059 |
| GSE37065 | Down | -0.8453180866 |
| GSE28863_A1 | Down | -0.2724354522 |
| GSE28863_A2 | Down | -0.1829172696 |
| GSE28863_A3 | Down | -0.1223319483 |
| GSE28863_A4 | Up | 0.0562029381 |
| GSE48662 | Down | -0.9003633976 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-20b-5p | MIMAT0001413 | MIRT006337 | Luciferase reporter assay | Functional MTI | 22438230 |
| hsa-miR-204-5p | MIMAT0000265 | MIRT007101 | Luciferase reporter assay//qRT-PCR//Western blot | Functional MTI | 23204229 |
| hsa-miR-375 | MIMAT0000728 | MIRT020031 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-218-5p | MIMAT0000275 | MIRT024211 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024662 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026948 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027181 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-96-5p | MIMAT0000095 | MIRT027920 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT032048 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043356 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
