HCSGD entry for EFNA3
1. General information
| Official gene symbol | EFNA3 |
|---|---|
| Entrez ID | 1944 |
| Gene full name | ephrin-A3 |
| Other gene symbols | EFL2 EPLG3 Ehk1-L LERK3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005005 | Transmembrane-ephrin receptor activity | TAS | molecular_function |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0006468 | Protein phosphorylation | TAS | biological_process |
| GO:0007267 | Cell-cell signaling | TAS | biological_process |
| GO:0008152 | Metabolic process | TAS | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0016310 | Phosphorylation | TAS | biological_process |
| GO:0018108 | Peptidyl-tyrosine phosphorylation | TAS | biological_process |
| GO:0031225 | Anchored component of membrane | IEA | cellular_component |
| GO:0046875 | Ephrin receptor binding | IPI | molecular_function |
| GO:0048013 | Ephrin receptor signaling pathway | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8669528931 | 0.2893784773 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3555418898 |
| GSE13712_SHEAR | Down | -0.6919084308 |
| GSE13712_STATIC | Down | -0.2821587106 |
| GSE19018 | Up | 0.0979862933 |
| GSE19899_A1 | Up | 0.0063669977 |
| GSE19899_A2 | Down | -0.0834451458 |
| PubMed_21979375_A1 | Up | 0.1262742570 |
| PubMed_21979375_A2 | Down | -0.1092769262 |
| GSE35957 | Down | -0.0216945488 |
| GSE36640 | Up | 0.0398408689 |
| GSE54402 | Up | 0.0103253047 |
| GSE9593 | Down | -0.0550074735 |
| GSE43922 | Up | 0.0190418453 |
| GSE24585 | Down | -0.0882375436 |
| GSE37065 | Up | 0.0737337276 |
| GSE28863_A1 | Down | -0.2963021222 |
| GSE28863_A2 | Down | -0.0168937598 |
| GSE28863_A3 | Up | 0.3117529410 |
| GSE28863_A4 | Up | 0.0739381764 |
| GSE48662 | Up | 0.2207707035 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-210-3p | MIMAT0000267 | MIRT002024 | Luciferase reporter assay | Functional MTI | 18539147 |
| hsa-miR-210-3p | MIMAT0000267 | MIRT002024 | Luciferase reporter assay//Reporter assay;Other | Functional MTI | 18417479 |
| hsa-miR-210-3p | MIMAT0000267 | MIRT002024 | immunoprecipitaion//qRT-PCR | Functional MTI (Weak) | 19826008 |
| hsa-miR-210-3p | MIMAT0000267 | MIRT002024 | Luciferase reporter assay//Western blot | Functional MTI | 19551852 |
| hsa-miR-210-3p | MIMAT0000267 | MIRT002024 | Luciferase reporter assay//Western blot | Functional MTI | 23322395 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
