HCSGD entry for EEF1A2
1. General information
| Official gene symbol | EEF1A2 |
|---|---|
| Entrez ID | 1917 |
| Gene full name | eukaryotic translation elongation factor 1 alpha 2 |
| Other gene symbols | EEF1AL EF-1-alpha-2 EF1A HS1 STN STNL |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003746 | Translation elongation factor activity | IEA | molecular_function |
| GO:0003924 | GTPase activity | IEA | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005853 | Eukaryotic translation elongation factor 1 complex | IEA | cellular_component |
| GO:0008135 | Translation factor activity, nucleic acid binding | NAS | molecular_function |
| GO:0010035 | Response to inorganic substance | IEA | biological_process |
| GO:0043025 | Neuronal cell body | IEA | cellular_component |
| GO:1900119 | Positive regulation of execution phase of apoptosis | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1201244596 | 0.1491886137 | 0.7089228475 | 0.7468226512 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1711745929 |
| GSE13712_SHEAR | Down | -3.7797058103 |
| GSE13712_STATIC | Down | -2.3874195490 |
| GSE19018 | Up | 0.1880697165 |
| GSE19899_A1 | Down | -0.1466613404 |
| GSE19899_A2 | Up | 1.3772396868 |
| PubMed_21979375_A1 | Down | -0.0302646763 |
| PubMed_21979375_A2 | Up | 2.1989454405 |
| GSE35957 | Up | 0.1479239549 |
| GSE36640 | Up | 0.2549861067 |
| GSE54402 | Up | 0.0801853462 |
| GSE9593 | Down | -0.0090460620 |
| GSE43922 | Up | 0.0945322773 |
| GSE24585 | Up | 0.2167734191 |
| GSE37065 | Down | -0.0192088945 |
| GSE28863_A1 | Up | 0.0102010744 |
| GSE28863_A2 | Up | 0.2371347349 |
| GSE28863_A3 | Down | -0.1076065507 |
| GSE28863_A4 | Down | -0.0441683943 |
| GSE48662 | Down | -0.4790673908 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020876 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024775 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026692 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-342-3p | MIMAT0000753 | MIRT043720 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 2 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 17266044 | The lines overexpressed EEF1A2, SMARA3 and STAT1 and underexpressed other oncogenes, tumor suppressors and extracellular matrix/adhesion genes |
| 2483690 | Nucleotide sequence analysis of the partial cDNA clone has led to the identification of pSEN as elongation factor I alpha |
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