HCSGD entry for S1PR3

1. General information

Official gene symbolS1PR3
Entrez ID1903
Gene full namesphingosine-1-phosphate receptor 3
Other gene symbolsEDG-3 EDG3 LPB3 S1P3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001816Cytokine productionIEAbiological_process
GO:0004930G-protein coupled receptor activityTASmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006954Inflammatory responseIEAbiological_process
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007193Adenylate cyclase-inhibiting G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0007204Positive regulation of cytosolic calcium ion concentrationTASbiological_process
GO:0008284Positive regulation of cell proliferationTASbiological_process
GO:0008289Lipid bindingTASmolecular_function
GO:0009653Anatomical structure morphogenesisTASbiological_process
GO:0032651Regulation of interleukin-1 beta productionIEAbiological_process
GO:0038036Sphingosine-1-phosphate receptor activityIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.07821840360.06818112910.59024845180.4928853337

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.9238973533
GSE13712_SHEARUp1.6724678201
GSE13712_STATICUp1.3835477144
GSE19018Down-0.6342705433
GSE19899_A1Down-0.4147470807
GSE19899_A2Down-1.0524406618
PubMed_21979375_A1Down-0.2772451909
PubMed_21979375_A2Down-1.2299383134
GSE35957Down-1.1558314961
GSE36640Down-0.0420037795
GSE54402Up0.6156183179
GSE9593Up0.3893843528
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-1.0078850182

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.