HCSGD entry for ECHS1
1. General information
| Official gene symbol | ECHS1 |
|---|---|
| Entrez ID | 1892 |
| Gene full name | enoyl CoA hydratase, short chain, 1, mitochondrial |
| Other gene symbols | SCEH |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004300 | Enoyl-CoA hydratase activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005739 | Mitochondrion | IDA TAS | cellular_component |
| GO:0005759 | Mitochondrial matrix | TAS | cellular_component |
| GO:0006635 | Fatty acid beta-oxidation | IEA TAS | biological_process |
| GO:0044255 | Cellular lipid metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3438905475 | 0.7322693097 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3515187006 |
| GSE13712_SHEAR | Down | -0.2120945107 |
| GSE13712_STATIC | Down | -0.0094132468 |
| GSE19018 | Up | 0.4134071060 |
| GSE19899_A1 | Down | -0.1192289201 |
| GSE19899_A2 | Up | 0.2645113374 |
| PubMed_21979375_A1 | Up | 0.4080072324 |
| PubMed_21979375_A2 | Up | 0.3321054593 |
| GSE35957 | Down | -0.2473183589 |
| GSE36640 | Down | -0.0860547074 |
| GSE54402 | Up | 0.4155272341 |
| GSE9593 | Up | 0.1291487943 |
| GSE43922 | Down | -0.0180913593 |
| GSE24585 | Down | -0.1978585173 |
| GSE37065 | Down | -0.1711600357 |
| GSE28863_A1 | Up | 0.0528725956 |
| GSE28863_A2 | Down | -0.0709259978 |
| GSE28863_A3 | Down | -0.0183714603 |
| GSE28863_A4 | Up | 0.0942420507 |
| GSE48662 | Down | -0.1409811564 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Hexanoyl-Coenzyme A | DB02563 | EXPT01799 |
| Octanoyl-Coenzyme A | DB02910 | EXPT00977 |
| Acetoacetyl-Coenzyme A | DB03059 | EXPT00820 |
| 4-(N,N-Dimethylamino)Cinnamoyl-Coa | DB04117 | EXPT01108 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023625 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045094 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-152-3p | MIMAT0000438 | MIRT045819 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-15b-5p | MIMAT0000417 | MIRT046438 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
