HCSGD entry for TYMP

1. General information

Official gene symbolTYMP
Entrez ID1890
Gene full namethymidine phosphorylase
Other gene symbolsECGF ECGF1 MEDPS1 MNGIE MTDPS1 PDECGF TP hPD-ECGF
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000002Mitochondrial genome maintenanceTASbiological_process
GO:0001525AngiogenesisIEAbiological_process
GO:0004645Phosphorylase activityIEAmolecular_function
GO:0005161Platelet-derived growth factor receptor bindingTASmolecular_function
GO:0005829CytosolTAScellular_component
GO:0006206Pyrimidine nucleobase metabolic processIEA TASbiological_process
GO:0006213Pyrimidine nucleoside metabolic processIEAbiological_process
GO:0006220Pyrimidine nucleotide metabolic processTASbiological_process
GO:0006260DNA replicationTASbiological_process
GO:0006935ChemotaxisIEAbiological_process
GO:0008083Growth factor activityIEAmolecular_function
GO:0009032Thymidine phosphorylase activityIEAmolecular_function
GO:0016154Pyrimidine-nucleoside phosphorylase activityIEAmolecular_function
GO:0016763Transferase activity, transferring pentosyl groupsEXP IEAmolecular_function
GO:0030154Cell differentiationIEAbiological_process
GO:0043097Pyrimidine nucleoside salvageTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046135Pyrimidine nucleoside catabolic processTASbiological_process
GO:0055086Nucleobase-containing small molecule metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.06336099690.62615121010.54299638671.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0896283628
GSE13712_SHEARUp1.1046632081
GSE13712_STATICUp1.4256574731
GSE19018Down-0.0971577978
GSE19899_A1Down-0.0440075485
GSE19899_A2Up0.1295906419
PubMed_21979375_A1Down-0.7702094822
PubMed_21979375_A2Down-0.0994759231
GSE35957Down-1.2218470870
GSE36640Up0.0881670984
GSE54402Down-0.1088824258
GSE9593Down-0.2595140550
GSE43922Up0.0564230348
GSE24585Up0.0765090196
GSE37065Up0.6181249869
GSE28863_A1Up0.0682259205
GSE28863_A2Up0.2181254112
GSE28863_A3Up0.3424071041
GSE28863_A4Up0.1339908811
GSE48662Up0.9125354960

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

5-Chloro-6-[(2-Iminopyrrolidin-1-Yl)Methyl]Pyrimidine-2,4(1h,3h)-DioneDB02631 EXPT00961

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-92a-3pMIMAT0000092MIRT048951CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.