HCSGD entry for APLNR
1. General information
| Official gene symbol | APLNR |
|---|---|
| Entrez ID | 187 |
| Gene full name | apelin receptor |
| Other gene symbols | AGTRL1 APJ APJR HG11 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004872 | Receptor activity | TAS | molecular_function |
| GO:0004930 | G-protein coupled receptor activity | IEA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0007186 | G-protein coupled receptor signaling pathway | TAS | biological_process |
| GO:0007507 | Heart development | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7439900232 | 0.1451241252 | 0.9999902473 | 0.7344380119 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0244453061 |
| GSE13712_SHEAR | Down | -6.1515021626 |
| GSE13712_STATIC | Down | -0.1776217080 |
| GSE19018 | Up | 0.0958851993 |
| GSE19899_A1 | Up | 0.0803487631 |
| GSE19899_A2 | Up | 0.0303641352 |
| PubMed_21979375_A1 | Up | 0.1418836808 |
| PubMed_21979375_A2 | Up | 0.2259000910 |
| GSE35957 | Up | 0.0987829262 |
| GSE36640 | Down | -0.0202729907 |
| GSE54402 | Down | -0.0126395021 |
| GSE9593 | Up | 0.0007567025 |
| GSE43922 | Up | 0.1812561994 |
| GSE24585 | Down | -0.0099323140 |
| GSE37065 | Down | -0.1357162761 |
| GSE28863_A1 | Down | -0.0561065189 |
| GSE28863_A2 | Down | -0.1663113597 |
| GSE28863_A3 | Up | 0.0829967912 |
| GSE28863_A4 | Up | 0.0854635588 |
| GSE48662 | Up | 0.1319984974 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-10b-5p | MIMAT0000254 | MIRT047418 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051137 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
