HCSGD entry for DUSP9
1. General information
| Official gene symbol | DUSP9 |
|---|---|
| Entrez ID | 1852 |
| Gene full name | dual specificity phosphatase 9 |
| Other gene symbols | MKP-4 MKP4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000188 | Inactivation of MAPK activity | IBA | biological_process |
| GO:0004721 | Phosphoprotein phosphatase activity | TAS | molecular_function |
| GO:0004725 | Protein tyrosine phosphatase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | TAS | cellular_component |
| GO:0005737 | Cytoplasm | TAS | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005829 | Cytosol | IBA | cellular_component |
| GO:0006470 | Protein dephosphorylation | IBA | biological_process |
| GO:0007254 | JNK cascade | TAS | biological_process |
| GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity | IBA IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4305625812 | 0.8987604916 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0414494575 |
| GSE13712_SHEAR | Up | 0.1958133496 |
| GSE13712_STATIC | Up | 0.1061397526 |
| GSE19018 | Down | -0.0394615548 |
| GSE19899_A1 | Up | 0.0542004614 |
| GSE19899_A2 | Down | -0.1718978197 |
| PubMed_21979375_A1 | Up | 0.1872230188 |
| PubMed_21979375_A2 | Down | -0.0199194231 |
| GSE35957 | Up | 0.2475805116 |
| GSE36640 | Down | -0.0446849985 |
| GSE54402 | Up | 0.1516274286 |
| GSE9593 | Down | -0.2523099858 |
| GSE43922 | Up | 0.1675358880 |
| GSE24585 | Up | 0.0808681672 |
| GSE37065 | Down | -0.0762862843 |
| GSE28863_A1 | Down | -0.0532039757 |
| GSE28863_A2 | Down | -0.0045150820 |
| GSE28863_A3 | Up | 0.2850093485 |
| GSE28863_A4 | Up | 0.0349417080 |
| GSE48662 | Up | 0.1567251416 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-98-5p | MIMAT0000096 | MIRT027506 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
