HCSGD entry for DTYMK

1. General information

Official gene symbolDTYMK
Entrez ID1841
Gene full namedeoxythymidylate kinase (thymidylate kinase)
Other gene symbolsCDC8 PP3731 TMPK TYMK
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004798Thymidylate kinase activityIDA IEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005758Mitochondrial intermembrane spaceIEAcellular_component
GO:0005759Mitochondrial matrixIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006233DTDP biosynthetic processIEAbiological_process
GO:0006235DTTP biosynthetic processIEAbiological_process
GO:0007049Cell cycleTASbiological_process
GO:0008283Cell proliferationTASbiological_process
GO:0015949Nucleobase-containing small molecule interconversionTASbiological_process
GO:0016301Kinase activityIEAmolecular_function
GO:0043627Response to estrogenIEAbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045445Myoblast differentiationIEAbiological_process
GO:0046686Response to cadmium ionIEAbiological_process
GO:0046939Nucleotide phosphorylationIDA TASbiological_process
GO:0046940Nucleoside monophosphate phosphorylationEXPbiological_process
GO:0050145Nucleoside phosphate kinase activityEXPmolecular_function
GO:0055086Nucleobase-containing small molecule metabolic processTASbiological_process
GO:0071363Cellular response to growth factor stimulusIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.99626640330.01450793280.99999024730.2367410415

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0405319172
GSE13712_SHEARDown-0.0895649228
GSE13712_STATICDown-0.0958502855
GSE19018Up0.0020003213
GSE19899_A1Down-0.3382455873
GSE19899_A2Down-0.4535871726
PubMed_21979375_A1Down-0.1196077354
PubMed_21979375_A2Down-0.7313160276
GSE35957Down-0.5595648433
GSE36640Down-1.1080823549
GSE54402Down-0.0238004092
GSE9593Down-0.4539086481
GSE43922Down-0.0272986930
GSE24585Down-0.1074200117
GSE37065Down-0.4336072919
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.6427243599

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

2',3'-Dideoxythymidine-5'-MonophosphateDB03150 EXPT00113
Phosphoric Acid Mono-[3-Fluoro-5-(5-Methyl-2,4-Dioxo-3,4-Dihydro-2h-Pyrimidin-1-Yl)-Tetrahyro-Furan-2-Ylmethyl] EsterDB03195 EXPT01414
Phosphoric Acid Mono-[3-Amino-5-(5-Methyl-2,4-Dioxo-3,4-Dihydro-2h-Pyrimidin-1-Yl)-Tetrahydro-Furan-2-Ylmethyl] EsterDB03233 EXPT02401
P1-(5'-Adenosyl)P5-(5'-Thymidyl)PentaphosphateDB03280 EXPT02996
3'-Azido-3'-Deoxythymidine-5'-MonophosphateDB03666 EXPT00583
P1-(5'-Adenosyl)P5-(5'-(3'azido-3'-Deoxythymidyl))PentaphosphateDB03845 EXPT03281
Phosphoaminophosphonic Acid-Adenylate EsterDB04395 EXPT00524

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-34a-5pMIMAT0000255MIRT025515ProteomicsFunctional MTI (Weak)21566225
hsa-miR-7-5pMIMAT0000252MIRT025947MicroarrayFunctional MTI (Weak)19073608
hsa-miR-183-5pMIMAT0000261MIRT047109CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.