HCSGD entry for DSG1
1. General information
| Official gene symbol | DSG1 |
|---|---|
| Entrez ID | 1828 |
| Gene full name | desmoglein 1 |
| Other gene symbols | CDHF4 DG1 DSG PPKS1 SPPK1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005509 | Calcium ion binding | IEA NAS | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005911 | Cell-cell junction | IDA | cellular_component |
| GO:0006915 | Apoptotic process | TAS | biological_process |
| GO:0006921 | Cellular component disassembly involved in execution phase of apoptosis | TAS | biological_process |
| GO:0007043 | Cell-cell junction assembly | NAS | biological_process |
| GO:0007156 | Homophilic cell adhesion | IEA | biological_process |
| GO:0009898 | Cytoplasmic side of plasma membrane | IDA | cellular_component |
| GO:0015643 | Toxic substance binding | NAS | molecular_function |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016324 | Apical plasma membrane | IEA | cellular_component |
| GO:0016328 | Lateral plasma membrane | IEA | cellular_component |
| GO:0016337 | Cell-cell adhesion | NAS | biological_process |
| GO:0016339 | Calcium-dependent cell-cell adhesion | NAS | biological_process |
| GO:0030057 | Desmosome | NAS | cellular_component |
| GO:0032570 | Response to progesterone | IEA | biological_process |
| GO:0045295 | Gamma-catenin binding | IPI | molecular_function |
| GO:0050821 | Protein stabilization | IDA | biological_process |
| GO:0060135 | Maternal process involved in female pregnancy | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4526538467 | 0.9282308689 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1338420187 |
| GSE13712_SHEAR | Up | 0.1327995071 |
| GSE13712_STATIC | Down | -0.1503335975 |
| GSE19018 | Down | -0.0294186711 |
| GSE19899_A1 | Up | 0.0263678228 |
| GSE19899_A2 | Down | -0.1341358962 |
| PubMed_21979375_A1 | Up | 0.3185190618 |
| PubMed_21979375_A2 | Down | -0.0333415784 |
| GSE35957 | Up | 0.0695877588 |
| GSE36640 | Up | 0.0804638880 |
| GSE54402 | Up | 0.1441956898 |
| GSE9593 | Up | 0.1991645542 |
| GSE43922 | Up | 0.1033146066 |
| GSE24585 | Down | -0.1549742908 |
| GSE37065 | Up | 0.0639062881 |
| GSE28863_A1 | Up | 0.0300850931 |
| GSE28863_A2 | Down | -0.0126992484 |
| GSE28863_A3 | Up | 0.1313546118 |
| GSE28863_A4 | Up | 0.0591953008 |
| GSE48662 | Up | 0.1317799144 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-148b-3p | MIMAT0000759 | MIRT019462 | Microarray | Functional MTI (Weak) | 17612493 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
