HCSGD entry for DRD1

1. General information

Official gene symbolDRD1
Entrez ID1812
Gene full namedopamine receptor D1
Other gene symbolsDADR DRD1A
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001588Dopamine neurotransmitter receptor activity, coupled via GsIDA IMPmolecular_function
GO:0001659Temperature homeostasisIEAbiological_process
GO:0001661Conditioned taste aversionIEAbiological_process
GO:0001662Behavioral fear responseIEAbiological_process
GO:0001963Synaptic transmission, dopaminergicIEAbiological_process
GO:0001975Response to amphetamineIEAbiological_process
GO:0004952Dopamine neurotransmitter receptor activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005789Endoplasmic reticulum membraneIEAcellular_component
GO:0005886Plasma membraneIDA TAScellular_component
GO:0005887Integral component of plasma membraneICcellular_component
GO:0006606Protein import into nucleusIEAbiological_process
GO:0007187G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messengerIDAbiological_process
GO:0007189Adenylate cyclase-activating G-protein coupled receptor signaling pathwayIDAbiological_process
GO:0007190Activation of adenylate cyclase activityIDAbiological_process
GO:0007191Adenylate cyclase-activating dopamine receptor signaling pathwayIDAbiological_process
GO:0007416Synapse assemblyISSbiological_process
GO:0007613MemoryIEAbiological_process
GO:0007617Mating behaviorISSbiological_process
GO:0007625Grooming behaviorIEAbiological_process
GO:0007628Adult walking behaviorISSbiological_process
GO:0008542Visual learningISSbiological_process
GO:0010579Positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0014002Astrocyte developmentIEAbiological_process
GO:0015872Dopamine transportIEAbiological_process
GO:0019226Transmission of nerve impulseISSbiological_process
GO:0019228Neuronal action potentialIEAbiological_process
GO:0021542Dentate gyrus developmentIEAbiological_process
GO:0021756Striatum developmentIEAbiological_process
GO:0021853Cerebral cortex GABAergic interneuron migrationISSbiological_process
GO:0030335Positive regulation of cell migrationISSbiological_process
GO:0030432PeristalsisIEAbiological_process
GO:0030819Positive regulation of cAMP biosynthetic processIDAbiological_process
GO:0035106Operant conditioningIEAbiological_process
GO:0035240Dopamine bindingIMPmolecular_function
GO:0042053Regulation of dopamine metabolic processIEAbiological_process
GO:0042311VasodilationIEAbiological_process
GO:0042417Dopamine metabolic processICbiological_process
GO:0042493Response to drugISSbiological_process
GO:0042711Maternal behaviorIEAbiological_process
GO:0043268Positive regulation of potassium ion transportISSbiological_process
GO:0046323Glucose importIEAbiological_process
GO:0046959HabituationIEAbiological_process
GO:0046960SensitizationIEAbiological_process
GO:0048148Behavioral response to cocaineIEAbiological_process
GO:0051281Positive regulation of release of sequestered calcium ion into cytosolIDAbiological_process
GO:0051482Positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathwayIDAbiological_process
GO:0051584Regulation of dopamine uptake involved in synaptic transmissionICbiological_process
GO:0051968Positive regulation of synaptic transmission, glutamatergicISSbiological_process
GO:0060134Prepulse inhibitionISSbiological_process
GO:0060158Phospholipase C-activating dopamine receptor signaling pathwayIDA IGIbiological_process
GO:0060291Long-term synaptic potentiationIEAbiological_process
GO:0060292Long term synaptic depressionIEAbiological_process
GO:0071870Cellular response to catecholamine stimulusIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.74822624140.65198249310.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0297173516
GSE13712_SHEARUp0.0350473053
GSE13712_STATICDown-0.0743502651
GSE19018Up0.0030411342
GSE19899_A1Up0.0146094377
GSE19899_A2Down-0.5306192960
PubMed_21979375_A1Up0.1435213140
PubMed_21979375_A2Down-0.1923885013
GSE35957Up0.0519538433
GSE36640Up0.2589541837
GSE54402Down-0.0358018702
GSE9593Down-0.0559844734
GSE43922Down-0.0472477620
GSE24585Up0.2304183584
GSE37065Down-0.0665244429
GSE28863_A1Down-0.0002885343
GSE28863_A2Up0.0860752219
GSE28863_A3Up0.2409878797
GSE28863_A4Up0.0200790483
GSE48662Up0.0623711438

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-504-5pMIMAT0002875MIRT000044Luciferase reporter assayFunctional MTI19135651
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.