HCSGD entry for DOM3Z
1. General information
| Official gene symbol | DOM3Z |
|---|---|
| Entrez ID | 1797 |
| Gene full name | dom-3 homolog Z (C. elegans) |
| Other gene symbols | DOM3L NG6 RAI1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0000287 | Magnesium ion binding | ISS | molecular_function |
| GO:0003729 | MRNA binding | ISS | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006402 | MRNA catabolic process | ISS | biological_process |
| GO:0008152 | Metabolic process | ISS | biological_process |
| GO:0008409 | 5'-3' exonuclease activity | ISS | molecular_function |
| GO:0034353 | RNA pyrophosphohydrolase activity | ISS | molecular_function |
| GO:0050779 | RNA destabilization | ISS | biological_process |
| GO:0071028 | Nuclear mRNA surveillance | ISS | biological_process |
| GO:0090305 | Nucleic acid phosphodiester bond hydrolysis | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9961041070 | 0.0111355686 | 0.9999902473 | 0.2084632290 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0334305892 |
| GSE13712_SHEAR | Down | -0.3844452180 |
| GSE13712_STATIC | Down | -0.7359883607 |
| GSE19018 | Up | 0.0815558127 |
| GSE19899_A1 | Down | -0.3052196067 |
| GSE19899_A2 | Down | -0.6586526133 |
| PubMed_21979375_A1 | Down | -0.8879200079 |
| PubMed_21979375_A2 | Down | -0.9037694939 |
| GSE35957 | Down | -0.3453198757 |
| GSE36640 | Down | -0.1248592808 |
| GSE54402 | Down | -0.3749178661 |
| GSE9593 | Down | -0.1626065123 |
| GSE43922 | Down | -0.0923284978 |
| GSE24585 | Down | -0.4313125778 |
| GSE37065 | Down | -0.1209280908 |
| GSE28863_A1 | Up | 0.0303129519 |
| GSE28863_A2 | Down | -0.2127622974 |
| GSE28863_A3 | Down | -0.1639880756 |
| GSE28863_A4 | Down | -0.3401877030 |
| GSE48662 | Up | 0.2375796105 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-615-3p | MIMAT0003283 | MIRT040304 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
