HCSGD entry for DOCK3
1. General information
| Official gene symbol | DOCK3 |
|---|---|
| Entrez ID | 1795 |
| Gene full name | dedicator of cytokinesis 3 |
| Other gene symbols | MOCA PBP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005085 | Guanyl-nucleotide exchange factor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0007264 | Small GTPase mediated signal transduction | IEA | biological_process |
| GO:0017124 | SH3 domain binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6927715170 | 0.0420991642 | 0.9999902473 | 0.3858259401 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1065982248 |
| GSE13712_SHEAR | Down | -0.0513574735 |
| GSE13712_STATIC | Up | 0.0825350594 |
| GSE19018 | Up | 0.0110969822 |
| GSE19899_A1 | Down | -0.0409745674 |
| GSE19899_A2 | Down | -0.1151370866 |
| PubMed_21979375_A1 | Up | 0.5475334586 |
| PubMed_21979375_A2 | Down | -0.2937652045 |
| GSE35957 | Down | -0.0055634196 |
| GSE36640 | Down | -0.0543190708 |
| GSE54402 | Up | 0.1007227593 |
| GSE9593 | Up | 0.2904001454 |
| GSE43922 | Up | 0.1025702960 |
| GSE24585 | Up | 0.0188329852 |
| GSE37065 | Up | 0.2033549329 |
| GSE28863_A1 | Down | -1.2707919210 |
| GSE28863_A2 | Up | 0.0792496304 |
| GSE28863_A3 | Down | -1.3042887943 |
| GSE28863_A4 | Down | -0.5171827893 |
| GSE48662 | Down | -0.0377643828 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-186-5p | MIMAT0000456 | MIRT045048 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
