HCSGD entry for AGL
1. General information
| Official gene symbol | AGL |
|---|---|
| Entrez ID | 178 |
| Gene full name | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase |
| Other gene symbols | GDE |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004133 | Glycogen debranching enzyme activity | TAS | molecular_function |
| GO:0004134 | 4-alpha-glucanotransferase activity | IBA | molecular_function |
| GO:0004135 | Amylo-alpha-1,6-glucosidase activity | IBA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | TAS | biological_process |
| GO:0005978 | Glycogen biosynthetic process | IEA | biological_process |
| GO:0005980 | Glycogen catabolic process | IBA TAS | biological_process |
| GO:0006006 | Glucose metabolic process | TAS | biological_process |
| GO:0007584 | Response to nutrient | IEA | biological_process |
| GO:0016234 | Inclusion body | IEA | cellular_component |
| GO:0016529 | Sarcoplasmic reticulum | IEA | cellular_component |
| GO:0030247 | Polysaccharide binding | IEA | molecular_function |
| GO:0031593 | Polyubiquitin binding | IEA | molecular_function |
| GO:0043033 | Isoamylase complex | TAS | cellular_component |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0051384 | Response to glucocorticoid | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9046843509 | 0.0068459139 | 0.9999902473 | 0.1653088342 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4415444660 |
| GSE13712_SHEAR | Down | -0.3863932266 |
| GSE13712_STATIC | Up | 0.2040287588 |
| GSE19018 | Up | 0.2188460905 |
| GSE19899_A1 | Down | -0.9836107557 |
| GSE19899_A2 | Down | -0.7265420776 |
| PubMed_21979375_A1 | Down | -1.1057472334 |
| PubMed_21979375_A2 | Down | -0.7089726096 |
| GSE35957 | Up | 0.1935192529 |
| GSE36640 | Up | 0.0523481327 |
| GSE54402 | Down | -0.8063743618 |
| GSE9593 | Down | -0.2951527872 |
| GSE43922 | Down | -0.5344770144 |
| GSE24585 | Up | 0.1701240107 |
| GSE37065 | Down | -0.1724959144 |
| GSE28863_A1 | Up | 0.5676336221 |
| GSE28863_A2 | Up | 0.7024177072 |
| GSE28863_A3 | Down | -0.5575530842 |
| GSE28863_A4 | Down | -0.5595626321 |
| GSE48662 | Down | -0.2135251403 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020541 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024894 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026198 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT028934 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032209 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-455-3p | MIMAT0004784 | MIRT037850 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041710 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-191-5p | MIMAT0000440 | MIRT045794 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
