HCSGD entry for DMRT1

1. General information

Official gene symbolDMRT1
Entrez ID1761
Gene full namedoublesex and mab-3 related transcription factor 1
Other gene symbolsDMT1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIEA ISSbiological_process
GO:0000902Cell morphogenesisIEAbiological_process
GO:0000987Core promoter proximal region sequence-specific DNA bindingIEA ISSmolecular_function
GO:0002176Male germ cell proliferationIEA ISSbiological_process
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005634NucleusIEA ISScellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0007283SpermatogenesisIEAbiological_process
GO:0007530Sex determinationTASbiological_process
GO:0008354Germ cell migrationIEAbiological_process
GO:0008584Male gonad developmentTASbiological_process
GO:0030238Male sex determinationIEA ISSbiological_process
GO:0035556Intracellular signal transductionIEAbiological_process
GO:0042803Protein homodimerization activityIEAmolecular_function
GO:0045835Negative regulation of meiosisIEA ISSbiological_process
GO:0045840Positive regulation of mitosisIEA ISSbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEA ISSbiological_process
GO:0046661Male sex differentiationISSbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0046982Protein heterodimerization activityIEAmolecular_function
GO:0048599Oocyte developmentIEAbiological_process
GO:0060008Sertoli cell differentiationISSbiological_process
GO:0060009Sertoli cell developmentIEAbiological_process
GO:0060903Positive regulation of meiosis IIEAbiological_process
GO:2000020Positive regulation of male gonad developmentIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.05479361730.93815947340.51135733521.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1999552592
GSE13712_SHEARUp1.8841663849
GSE13712_STATICUp1.3590840981
GSE19018Up0.0806716360
GSE19899_A1Down-0.1401849835
GSE19899_A2Up0.0258330983
PubMed_21979375_A1Up0.1225436964
PubMed_21979375_A2Up0.1122151174
GSE35957Down-0.0948763793
GSE36640Down-0.1101617837
GSE54402Up0.1238201949
GSE9593Down-0.0107977590
GSE43922Up0.0144841640
GSE24585Up0.3898456477
GSE37065Down-0.0987236096
GSE28863_A1Down-0.1162307212
GSE28863_A2Down-0.0203383228
GSE28863_A3Up0.3205401549
GSE28863_A4Up0.0333875566
GSE48662Up0.5139405347

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.