HCSGD entry for DLG2
1. General information
| Official gene symbol | DLG2 |
|---|---|
| Entrez ID | 1740 |
| Gene full name | discs, large homolog 2 (Drosophila) |
| Other gene symbols | PPP1R58 PSD-93 PSD93 chapsyn-110 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004385 | Guanylate kinase activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0007268 | Synaptic transmission | IEA | biological_process |
| GO:0008152 | Metabolic process | TAS | biological_process |
| GO:0010923 | Negative regulation of phosphatase activity | IDA | biological_process |
| GO:0014069 | Postsynaptic density | IEA | cellular_component |
| GO:0016310 | Phosphorylation | TAS | biological_process |
| GO:0019233 | Sensory perception of pain | IEA | biological_process |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0044224 | Juxtaparanode region of axon | IEA | cellular_component |
| GO:0045211 | Postsynaptic membrane | IEA | cellular_component |
| GO:0046939 | Nucleotide phosphorylation | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6079670301 | 0.8856178375 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0349142310 |
| GSE13712_SHEAR | Down | -0.0066468701 |
| GSE13712_STATIC | Up | 0.0803775232 |
| GSE19018 | Up | 0.1102761051 |
| GSE19899_A1 | Up | 0.0798342819 |
| GSE19899_A2 | Up | 0.0577750251 |
| PubMed_21979375_A1 | Up | 0.0508121768 |
| PubMed_21979375_A2 | Down | -0.0699117121 |
| GSE35957 | Up | 0.1970797404 |
| GSE36640 | Up | 0.1351936746 |
| GSE54402 | Up | 0.0253416028 |
| GSE9593 | Down | -0.0197277157 |
| GSE43922 | Up | 0.0087191115 |
| GSE24585 | Up | 0.0180056899 |
| GSE37065 | Down | -0.0436404698 |
| GSE28863_A1 | Down | -0.2359634232 |
| GSE28863_A2 | Up | 0.2429048249 |
| GSE28863_A3 | Up | 0.0808586915 |
| GSE28863_A4 | Up | 0.2232615083 |
| GSE48662 | Up | 0.0001685067 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017170 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-148b-3p | MIMAT0000759 | MIRT019305 | Microarray | Functional MTI (Weak) | 17612493 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
