HCSGD entry for SEPT1
1. General information
| Official gene symbol | SEPT1 |
|---|---|
| Entrez ID | 1731 |
| Gene full name | septin 1 |
| Other gene symbols | DIFF6 LARP PNUTL3 SEP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005815 | Microtubule organizing center | IEA | cellular_component |
| GO:0007049 | Cell cycle | IEA | biological_process |
| GO:0030496 | Midbody | IEA | cellular_component |
| GO:0031105 | Septin complex | IEA | cellular_component |
| GO:0051301 | Cell division | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9269089548 | 0.1326760115 | 0.9999902473 | 0.7013788512 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0159437815 |
| GSE13712_SHEAR | Down | -0.0127845110 |
| GSE13712_STATIC | Up | 0.0047519128 |
| GSE19018 | Down | -0.0208166386 |
| GSE19899_A1 | Down | -0.0026037247 |
| GSE19899_A2 | Down | -0.0968575870 |
| PubMed_21979375_A1 | Up | 0.1136239252 |
| PubMed_21979375_A2 | Down | -0.0171559469 |
| GSE35957 | Down | -0.2732268571 |
| GSE36640 | Down | -0.0773754669 |
| GSE54402 | Up | 0.0173566397 |
| GSE9593 | Up | 0.0185891099 |
| GSE43922 | Up | 0.0258656400 |
| GSE24585 | Up | 0.0062271817 |
| GSE37065 | Down | -0.1278032351 |
| GSE28863_A1 | Down | -0.5169119942 |
| GSE28863_A2 | Down | -0.6249769028 |
| GSE28863_A3 | Up | 0.0945771168 |
| GSE28863_A4 | Down | -0.0758647768 |
| GSE48662 | Up | 0.0232705430 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018775 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025436 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-320a | MIMAT0000510 | MIRT044485 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
