HCSGD entry for DIAPH2
1. General information
| Official gene symbol | DIAPH2 |
|---|---|
| Entrez ID | 1730 |
| Gene full name | diaphanous-related formin 2 |
| Other gene symbols | DIA DIA2 DRF2 POF POF2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000910 | Cytokinesis | TAS | biological_process |
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005102 | Receptor binding | TAS | molecular_function |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005769 | Early endosome | IEA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0005829 | Cytosol | IEA | cellular_component |
| GO:0007275 | Multicellular organismal development | IEA | biological_process |
| GO:0007292 | Female gamete generation | TAS | biological_process |
| GO:0017048 | Rho GTPase binding | IEA | molecular_function |
| GO:0030036 | Actin cytoskeleton organization | IEA | biological_process |
| GO:0030041 | Actin filament polymerization | IEA | biological_process |
| GO:0030154 | Cell differentiation | IEA | biological_process |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0048477 | Oogenesis | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2989032939 | 0.0225347783 | 0.9980459850 | 0.2889127618 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.7467921894 |
| GSE13712_SHEAR | Down | -0.3957078674 |
| GSE13712_STATIC | Up | 0.0246202129 |
| GSE19018 | Up | 1.2099117089 |
| GSE19899_A1 | Down | -0.7036149270 |
| GSE19899_A2 | Up | 0.3081795630 |
| PubMed_21979375_A1 | Down | -0.4735294265 |
| PubMed_21979375_A2 | Down | -0.3817346972 |
| GSE35957 | Up | 0.2337165357 |
| GSE36640 | Up | 0.5948124120 |
| GSE54402 | Down | -0.3892016191 |
| GSE9593 | Up | 0.2308909989 |
| GSE43922 | Down | -0.7399799759 |
| GSE24585 | Down | -0.5805540503 |
| GSE37065 | Up | 0.1622232886 |
| GSE28863_A1 | Up | 0.2386667504 |
| GSE28863_A2 | Up | 0.4098590426 |
| GSE28863_A3 | Down | -0.5878325652 |
| GSE28863_A4 | Up | 0.0061913880 |
| GSE48662 | Down | -0.4071545500 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-10b-5p | MIMAT0000254 | MIRT047452 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-3p | MIMAT0000071 | MIRT050782 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
