HCSGD entry for ZNF675


1. General information

Official gene symbolZNF675
Entrez ID171392
Gene full namezinc finger protein 675
Other gene symbolsTBZF TIZ
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0003676Nucleic acid bindingIEAmolecular_function
GO:0003677DNA bindingNASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005622IntracellularIEAcellular_component
GO:0005634NucleusIDAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0007249I-kappaB kinase/NF-kappaB signalingIDAbiological_process
GO:0008270Zinc ion bindingNASmolecular_function
GO:0010804Negative regulation of tumor necrosis factor-mediated signaling pathwayIDAbiological_process
GO:0019221Cytokine-mediated signaling pathwayIDAbiological_process
GO:0031625Ubiquitin protein ligase bindingIPImolecular_function
GO:0032088Negative regulation of NF-kappaB transcription factor activityIDAbiological_process
GO:0043508Negative regulation of JUN kinase activityIDAbiological_process
GO:0045453Bone resorptionTASbiological_process
GO:0045671Negative regulation of osteoclast differentiationIDAbiological_process
GO:0046329Negative regulation of JNK cascadeIDAbiological_process
GO:0048471Perinuclear region of cytoplasmIDAcellular_component
GO:2000660Negative regulation of interleukin-1-mediated signaling pathwayIDAbiological_process
GO:2000678Negative regulation of transcription regulatory region DNA bindingIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.75476199230.07658422170.99999024730.5228983917

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3327407694
GSE13712_SHEARUp0.2737449504
GSE13712_STATICUp0.1329107741
GSE19018Down-0.4880089278
GSE19899_A1Down-0.0315477517
GSE19899_A2Down-0.4204955206
PubMed_21979375_A1Down-0.2191426316
PubMed_21979375_A2Down-0.3940371160
GSE35957Down-0.4707775316
GSE36640Down-0.4357987994
GSE54402Down-0.4338608137
GSE9593Down-0.1761884053
GSE43922Down-0.2711284267
GSE24585Down-0.0831029827
GSE37065Up0.1787878106
GSE28863_A1Down-0.0772560943
GSE28863_A2Up0.2923885654
GSE28863_A3Down-0.2303929788
GSE28863_A4Up0.1170026907
GSE48662Up0.0679231709

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.