HCSGD entry for ADAMTS18

1. General information

Official gene symbolADAMTS18
Entrez ID170692
Gene full nameADAM metallopeptidase with thrombospondin type 1 motif, 18
Other gene symbolsADAMTS21 KNO2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004222Metalloendopeptidase activityIEAmolecular_function
GO:0005578Proteinaceous extracellular matrixIEAcellular_component
GO:0006508ProteolysisIEAbiological_process
GO:0007229Integrin-mediated signaling pathwayIEAbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.18907592040.44437029750.84702153531.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.7263696241
GSE13712_SHEARDown-2.4514595548
GSE13712_STATICDown-0.8173636497
GSE19018Up0.1435652080
GSE19899_A1Up0.0193467081
GSE19899_A2Up0.1915290628
PubMed_21979375_A1Up0.4500438776
PubMed_21979375_A2Up0.3481674878
GSE35957Up0.0750966328
GSE36640Up0.0791302990
GSE54402Up0.7701772377
GSE9593Down-0.0575111722
GSE43922Up0.0162634370
GSE24585Down-0.0679691855
GSE37065Down-0.0986672676
GSE28863_A1Down-0.0677047415
GSE28863_A2Down-0.0223803266
GSE28863_A3Up0.2355909434
GSE28863_A4Up0.1256244639
GSE48662Down-0.0803402882

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.