HCSGD entry for DHX36


1. General information

Official gene symbolDHX36
Entrez ID170506
Gene full nameDEAH (Asp-Glu-Ala-His) box polypeptide 36
Other gene symbolsDDX36 G4R1 MLEL1 RHAU
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003676Nucleic acid bindingIEAmolecular_function
GO:0003725Double-stranded RNA bindingIDA IEAmolecular_function
GO:0004386Helicase activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0008026ATP-dependent helicase activityIEAmolecular_function
GO:0009615Response to virusIEAbiological_process
GO:0032481Positive regulation of type I interferon productionTASbiological_process
GO:0043330Response to exogenous dsRNAIEAbiological_process
GO:0045087Innate immune responseTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.05638960530.78961075950.51572317581.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1528601375
GSE13712_SHEARUp0.3211988821
GSE13712_STATICUp0.0804494355
GSE19018Down-0.2746019162
GSE19899_A1Up0.3013077420
GSE19899_A2Up0.2929800123
PubMed_21979375_A1Up0.1310386734
PubMed_21979375_A2Up0.6434997615
GSE35957Down-0.3244076922
GSE36640Down-0.2613296486
GSE54402Up0.3115445807
GSE9593Up0.0337112454
GSE43922Up0.2093913629
GSE24585Down-0.0846256171
GSE37065Up0.2118006718
GSE28863_A1Up1.0428726866
GSE28863_A2Up0.8808074861
GSE28863_A3Down-0.2937395142
GSE28863_A4Down-0.3065647502
GSE48662Down-0.3004303741

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-30a-5pMIMAT0000087MIRT028475ProteomicsFunctional MTI (Weak)18668040
hsa-miR-16-5pMIMAT0000069MIRT031417ProteomicsFunctional MTI (Weak)18668040
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.