HCSGD entry for SLC30A8

1. General information

Official gene symbolSLC30A8
Entrez ID169026
Gene full namesolute carrier family 30 (zinc transporter), member 8
Other gene symbolsZNT8 ZnT-8
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005385Zinc ion transmembrane transporter activityIDAmolecular_function
GO:0005794Golgi apparatusIDAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0006829Zinc ion transportIDAbiological_process
GO:0006882Cellular zinc ion homeostasisIEA ISSbiological_process
GO:0008270Zinc ion bindingICmolecular_function
GO:0008324Cation transmembrane transporter activityIEAmolecular_function
GO:0009749Response to glucoseIEA IMPbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016023Cytoplasmic membrane-bounded vesicleIEA ISScellular_component
GO:0030073Insulin secretionIEA IMPbiological_process
GO:0030141Secretory granuleIDAcellular_component
GO:0030658Transport vesicle membraneIEAcellular_component
GO:0030667Secretory granule membraneTAScellular_component
GO:0032024Positive regulation of insulin secretionIEA ISSbiological_process
GO:0032119Sequestering of zinc ionIDAbiological_process
GO:0034220Ion transmembrane transportIDAbiological_process
GO:0034341Response to interferon-gammaIEAbiological_process
GO:0042593Glucose homeostasisISSbiological_process
GO:0042803Protein homodimerization activityIEA ISSmolecular_function
GO:0055085Transmembrane transportTASbiological_process
GO:0060627Regulation of vesicle-mediated transportIEA ISSbiological_process
GO:0061088Regulation of sequestering of zinc ionIEA ISSbiological_process
GO:0070555Response to interleukin-1IEAbiological_process
GO:0071577Zinc ion transmembrane transportIDAbiological_process
GO:0072511Divalent inorganic cation transportIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.80854912050.82300386380.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1156645366
GSE13712_SHEARUp0.0254253703
GSE13712_STATICDown-0.0757177212
GSE19018Up0.2773970196
GSE19899_A1Up0.0170342743
GSE19899_A2Up0.0845114445
PubMed_21979375_A1Down-0.0636660536
PubMed_21979375_A2Down-0.1402105923
GSE35957Up0.2214983101
GSE36640Down-0.0593453084
GSE54402Up0.0381880194
GSE9593Down-0.0864680805
GSE43922Up0.0195246227
GSE24585Up0.0948633259
GSE37065Down-0.0078464744
GSE28863_A1Down-0.0192083238
GSE28863_A2Up0.0839508898
GSE28863_A3Up0.0363962135
GSE28863_A4Up0.0355839512
GSE48662Down-0.0502297559

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.