HCSGD entry for DFNA5
1. General information
| Official gene symbol | DFNA5 |
|---|---|
| Entrez ID | 1687 |
| Gene full name | deafness, autosomal dominant 5 |
| Other gene symbols | ICERE-1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0007605 | Sensory perception of sound | TAS | biological_process |
| GO:0008285 | Negative regulation of cell proliferation | IDA | biological_process |
| GO:0060113 | Inner ear receptor cell differentiation | IEA | biological_process |
| GO:2001244 | Positive regulation of intrinsic apoptotic signaling pathway | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1362097033 | 0.1063840128 | 0.7448941616 | 0.6246115548 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.5873229296 |
| GSE13712_SHEAR | Up | 0.3774772817 |
| GSE13712_STATIC | Up | 0.4267303502 |
| GSE19018 | Up | 1.2014183413 |
| GSE19899_A1 | Down | -0.7409574391 |
| GSE19899_A2 | Up | 0.3517537629 |
| PubMed_21979375_A1 | Down | -0.1290818464 |
| PubMed_21979375_A2 | Up | 0.1383118107 |
| GSE35957 | Up | 0.4189280492 |
| GSE36640 | Down | -0.8067991627 |
| GSE54402 | Down | -0.2742364648 |
| GSE9593 | Up | 0.8223737217 |
| GSE43922 | Down | -0.1081428205 |
| GSE24585 | Up | 0.3840470555 |
| GSE37065 | Down | -0.0926471545 |
| GSE28863_A1 | Down | -0.0486166905 |
| GSE28863_A2 | Up | 0.0790861034 |
| GSE28863_A3 | Down | -0.5663586312 |
| GSE28863_A4 | Down | -0.1479660830 |
| GSE48662 | Down | -0.3820217586 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT024093 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030292 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
