HCSGD entry for DEFA6

1. General information

Official gene symbolDEFA6
Entrez ID1671
Gene full namedefensin, alpha 6, Paneth cell-specific
Other gene symbolsDEF6 HD-6
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005576Extracellular regionTAScellular_component
GO:0005615Extracellular spaceIEAcellular_component
GO:0005796Golgi lumenTAScellular_component
GO:0031640Killing of cells of other organismIEAbiological_process
GO:0042742Defense response to bacteriumIEAbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0050832Defense response to fungusIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.80864476650.44501669390.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1844509026
GSE13712_SHEARUp0.0311241534
GSE13712_STATICUp0.2310338204
GSE19018Up0.1438885807
GSE19899_A1Down-0.0051836658
GSE19899_A2Down-0.1829921898
PubMed_21979375_A1Up0.1007480303
PubMed_21979375_A2Down-0.3222990182
GSE35957Up0.1759529678
GSE36640Down-0.1052642190
GSE54402Up0.0224077230
GSE9593Up0.0399462629
GSE43922Up0.0228223474
GSE24585Down-0.2011279125
GSE37065Up0.0545602507
GSE28863_A1Down-0.0584546300
GSE28863_A2Down-0.2400220505
GSE28863_A3Up0.2615644371
GSE28863_A4Up0.0292730065
GSE48662Down-0.0695722788

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.