HCSGD entry for DDOST
1. General information
| Official gene symbol | DDOST |
|---|---|
| Entrez ID | 1650 |
| Gene full name | dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) |
| Other gene symbols | AGER1 CDG1R OKSWcl45 OST OST48 WBP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004576 | Oligosaccharyl transferase activity | ISS | molecular_function |
| GO:0004579 | Dolichyl-diphosphooligosaccharide-protein glycotransferase activity | IC IDA IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | IEA TAS | cellular_component |
| GO:0006412 | Translation | TAS | biological_process |
| GO:0006486 | Protein glycosylation | ISS | biological_process |
| GO:0006487 | Protein N-linked glycosylation | IDA | biological_process |
| GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | TAS | biological_process |
| GO:0008250 | Oligosaccharyltransferase complex | ISS TAS | cellular_component |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0018279 | Protein N-linked glycosylation via asparagine | IC IEA TAS | biological_process |
| GO:0034097 | Response to cytokine | IDA | biological_process |
| GO:0042110 | T cell activation | IDA | biological_process |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0043234 | Protein complex | IDA | cellular_component |
| GO:0043687 | Post-translational protein modification | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9285346871 | 0.2165589871 | 0.9999902473 | 0.8960932401 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0642836899 |
| GSE13712_SHEAR | Down | -0.1494094026 |
| GSE13712_STATIC | Down | -0.0881853114 |
| GSE19018 | Up | 0.1603015686 |
| GSE19899_A1 | Down | -0.1469648194 |
| GSE19899_A2 | Down | -0.0037734235 |
| PubMed_21979375_A1 | Down | -0.1524116736 |
| PubMed_21979375_A2 | Down | -0.3711772478 |
| GSE35957 | Down | -0.4813099491 |
| GSE36640 | Up | 0.1247661500 |
| GSE54402 | Down | -0.1578490270 |
| GSE9593 | Up | 0.0835429849 |
| GSE43922 | Down | -0.0488331787 |
| GSE24585 | Down | -0.0404966681 |
| GSE37065 | Down | -0.0552700026 |
| GSE28863_A1 | Up | 0.2333405943 |
| GSE28863_A2 | Up | 0.2881166658 |
| GSE28863_A3 | Down | -0.5369752690 |
| GSE28863_A4 | Down | -0.0870475841 |
| GSE48662 | Down | -0.0050060370 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-192-5p | MIMAT0000222 | MIRT004128 | Microarray | Functional MTI (Weak) | 16822819 |
| hsa-miR-324-3p | MIMAT0000762 | MIRT042867 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7i-5p | MIMAT0000415 | MIRT046554 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT047928 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
