HCSGD entry for DDC

1. General information

Official gene symbolDDC
Entrez ID1644
Gene full namedopa decarboxylase (aromatic L-amino acid decarboxylase)
Other gene symbolsAADC
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004058Aromatic-L-amino-acid decarboxylase activityIDA IEA TASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005829CytosolTAScellular_component
GO:0006520Cellular amino acid metabolic processIEAbiological_process
GO:0007623Circadian rhythmIEAbiological_process
GO:0008021Synaptic vesicleIEAcellular_component
GO:0010259Multicellular organismal agingIEAbiological_process
GO:0015842Synaptic vesicle amine transportIEAbiological_process
GO:0016597Amino acid bindingIEAmolecular_function
GO:0016831Carboxy-lyase activityIEAmolecular_function
GO:0019904Protein domain specific bindingIEAmolecular_function
GO:0030170Pyridoxal phosphate bindingIEAmolecular_function
GO:0030424AxonIEAcellular_component
GO:0033076Isoquinoline alkaloid metabolic processIEAbiological_process
GO:0034641Cellular nitrogen compound metabolic processTASbiological_process
GO:0035690Cellular response to drugIEAbiological_process
GO:0042416Dopamine biosynthetic processIEAbiological_process
GO:0042423Catecholamine biosynthetic processTASbiological_process
GO:0042427Serotonin biosynthetic processIEAbiological_process
GO:0043025Neuronal cell bodyIEAcellular_component
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046219Indolalkylamine biosynthetic processTASbiological_process
GO:0046684Response to pyrethroidIEAbiological_process
GO:0052314Phytoalexin metabolic processIEAbiological_process
GO:0071312Cellular response to alkaloidIEAbiological_process
GO:0071363Cellular response to growth factor stimulusIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.59440552790.89157042290.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2368117998
GSE13712_SHEARUp0.0570156408
GSE13712_STATICDown-0.0885811378
GSE19018Down-0.0595321445
GSE19899_A1Up0.1321556637
GSE19899_A2Up0.0702857982
PubMed_21979375_A1Up0.1970319805
PubMed_21979375_A2Up0.1374840076
GSE35957Up0.0521111632
GSE36640Up0.0626982865
GSE54402Up0.0068415030
GSE9593Up0.0014144325
GSE43922Up0.0140074274
GSE24585Up0.0050720390
GSE37065Up0.0343286121
GSE28863_A1Down-0.0938446024
GSE28863_A2Down-0.0857825327
GSE28863_A3Up0.1814515123
GSE28863_A4Up0.0829035515
GSE48662Down-0.1059227758

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

CHF-1512DB05307 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.