HCSGD entry for IFNLR1
1. General information
| Official gene symbol | IFNLR1 |
|---|---|
| Entrez ID | 163702 |
| Gene full name | interferon, lambda receptor 1 |
| Other gene symbols | CRF2/12 IFNLR IL-28R1 IL28RA LICR2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004896 | Cytokine receptor activity | NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0007165 | Signal transduction | NAS | biological_process |
| GO:0008285 | Negative regulation of cell proliferation | NAS | biological_process |
| GO:0016021 | Integral component of membrane | NAS | cellular_component |
| GO:0019221 | Cytokine-mediated signaling pathway | NAS | biological_process |
| GO:0032002 | Interleukin-28 receptor complex | IDA | cellular_component |
| GO:0050691 | Regulation of defense response to virus by host | IDA | biological_process |
| GO:0051607 | Defense response to virus | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4649900156 | 0.9314913985 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0072971501 |
| GSE13712_SHEAR | Up | 0.0465767741 |
| GSE13712_STATIC | Up | 0.0188004975 |
| GSE19018 | Up | 0.1811330826 |
| GSE19899_A1 | Up | 0.0375965177 |
| GSE19899_A2 | Up | 0.0571838872 |
| PubMed_21979375_A1 | Up | 0.0416237861 |
| PubMed_21979375_A2 | Up | 0.0197810565 |
| GSE35957 | Up | 0.1839075657 |
| GSE36640 | Up | 0.0378000832 |
| GSE54402 | Down | -0.0722746964 |
| GSE9593 | Up | 0.1384967545 |
| GSE43922 | Up | 0.0224304874 |
| GSE24585 | Up | 0.0501891446 |
| GSE37065 | Down | -0.0312099861 |
| GSE28863_A1 | Down | -0.0919907129 |
| GSE28863_A2 | Up | 0.0917349867 |
| GSE28863_A3 | Up | 0.2850579257 |
| GSE28863_A4 | Up | 0.2589641058 |
| GSE48662 | Down | -0.0440958498 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024759 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026809 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
