HCSGD entry for DENND1B
1. General information
| Official gene symbol | DENND1B |
|---|---|
| Entrez ID | 163486 |
| Gene full name | DENN/MADD domain containing 1B |
| Other gene symbols | C1ORF18 C1orf218 FAM31B |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005829 | Cytosol | IEA | cellular_component |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0017112 | Rab guanyl-nucleotide exchange factor activity | IDA | molecular_function |
| GO:0030136 | Clathrin-coated vesicle | IEA | cellular_component |
| GO:0032313 | Regulation of Rab GTPase activity | IDA | biological_process |
| GO:0032318 | Regulation of Ras GTPase activity | IDA | biological_process |
| GO:0043087 | Regulation of GTPase activity | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9758982220 | 0.0068363702 | 0.9999902473 | 0.1653088342 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1732321974 |
| GSE13712_SHEAR | Up | 0.0230944205 |
| GSE13712_STATIC | Up | 0.1071568698 |
| GSE19018 | Down | -0.1721155304 |
| GSE19899_A1 | Down | -0.0339503316 |
| GSE19899_A2 | Down | -0.6612965640 |
| PubMed_21979375_A1 | Down | -0.0583766948 |
| PubMed_21979375_A2 | Down | -0.3344850843 |
| GSE35957 | Down | -0.2205372769 |
| GSE36640 | Down | -0.0300058014 |
| GSE54402 | Down | -0.2918985411 |
| GSE9593 | Down | -0.1149952040 |
| GSE43922 | Down | -0.1270051337 |
| GSE24585 | Up | 0.3028999447 |
| GSE37065 | Up | 0.2218254977 |
| GSE28863_A1 | Down | -0.9523834813 |
| GSE28863_A2 | Down | -0.3555006604 |
| GSE28863_A3 | Down | -1.6240865044 |
| GSE28863_A4 | Down | -0.5302914905 |
| GSE48662 | Up | 0.0819813796 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
