HCSGD entry for DBN1
1. General information
| Official gene symbol | DBN1 |
|---|---|
| Entrez ID | 1627 |
| Gene full name | drebrin 1 |
| Other gene symbols | D0S117E |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003779 | Actin binding | IEA NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005522 | Profilin binding | IEA ISS | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0005737 | Cytoplasm | NAS | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0005921 | Gap junction | IEA | cellular_component |
| GO:0005938 | Cell cortex | IEA | cellular_component |
| GO:0007015 | Actin filament organization | IEA ISS | biological_process |
| GO:0010643 | Cell communication by chemical coupling | IEA | biological_process |
| GO:0010644 | Cell communication by electrical coupling | IEA | biological_process |
| GO:0015629 | Actin cytoskeleton | IEA ISS | cellular_component |
| GO:0030425 | Dendrite | NAS | cellular_component |
| GO:0032507 | Maintenance of protein location in cell | IEA | biological_process |
| GO:0042641 | Actomyosin | NAS | cellular_component |
| GO:0048168 | Regulation of neuronal synaptic plasticity | NAS | biological_process |
| GO:0048699 | Generation of neurons | IEA | biological_process |
| GO:0050773 | Regulation of dendrite development | NAS | biological_process |
| GO:0061351 | Neural precursor cell proliferation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2259921698 | 0.3398338513 | 0.9071739973 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0200947326 |
| GSE13712_SHEAR | Up | 0.0266445437 |
| GSE13712_STATIC | Up | 0.0105463047 |
| GSE19018 | Down | -0.0641394909 |
| GSE19899_A1 | Up | 0.0547906715 |
| GSE19899_A2 | Up | 0.5281121654 |
| PubMed_21979375_A1 | Up | 0.6949778557 |
| PubMed_21979375_A2 | Up | 0.7451490633 |
| GSE35957 | Up | 0.3808706209 |
| GSE36640 | Up | 0.2758283418 |
| GSE54402 | Up | 0.2803995518 |
| GSE9593 | Down | -0.1359373803 |
| GSE43922 | Down | -0.0313090724 |
| GSE24585 | Down | -0.8812684301 |
| GSE37065 | Down | -0.2546155386 |
| GSE28863_A1 | Down | -0.0371075987 |
| GSE28863_A2 | Down | -0.4561921542 |
| GSE28863_A3 | Up | 0.2604572624 |
| GSE28863_A4 | Down | -0.0799980958 |
| GSE48662 | Up | 0.1850828451 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020934 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1 | MIMAT0000416 | MIRT024053 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1 | MIMAT0000416 | MIRT024053 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT037119 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039919 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040871 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045157 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045543 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046733 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
