HCSGD entry for AP1B1
1. General information
| Official gene symbol | AP1B1 |
|---|---|
| Entrez ID | 162 |
| Gene full name | adaptor-related protein complex 1, beta 1 subunit |
| Other gene symbols | ADTB1 AP105A BAM22 CLAPB2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | TAS | cellular_component |
| GO:0005215 | Transporter activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005765 | Lysosomal membrane | TAS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006886 | Intracellular protein transport | IEA | biological_process |
| GO:0006892 | Post-Golgi vesicle-mediated transport | TAS | biological_process |
| GO:0008565 | Protein transporter activity | IEA | molecular_function |
| GO:0016032 | Viral process | TAS | biological_process |
| GO:0016192 | Vesicle-mediated transport | IEA | biological_process |
| GO:0019886 | Antigen processing and presentation of exogenous peptide antigen via MHC class II | TAS | biological_process |
| GO:0030117 | Membrane coat | IEA | cellular_component |
| GO:0030131 | Clathrin adaptor complex | IEA | cellular_component |
| GO:0030659 | Cytoplasmic vesicle membrane | TAS | cellular_component |
| GO:0030665 | Clathrin-coated vesicle membrane | IEA | cellular_component |
| GO:0032588 | Trans-Golgi network membrane | TAS | cellular_component |
| GO:0050690 | Regulation of defense response to virus by virus | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1894784697 | 0.8436924927 | 0.8470215353 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1447448853 |
| GSE13712_SHEAR | Up | 0.0328919728 |
| GSE13712_STATIC | Down | -0.3026073668 |
| GSE19018 | Up | 0.1874604772 |
| GSE19899_A1 | Down | -0.0136574547 |
| GSE19899_A2 | Up | 0.4469878073 |
| PubMed_21979375_A1 | Up | 0.6455406896 |
| PubMed_21979375_A2 | Up | 1.0410343301 |
| GSE35957 | Down | -0.0597263310 |
| GSE36640 | Down | -0.2043642421 |
| GSE54402 | Up | 0.3318189159 |
| GSE9593 | Down | -0.0697948647 |
| GSE43922 | Up | 0.0014520738 |
| GSE24585 | Up | 0.1767326171 |
| GSE37065 | Down | -0.1458588283 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.0192660386 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023555 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1 | MIMAT0000416 | MIRT023555 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-455-3p | MIMAT0004784 | MIRT037846 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-769-3p | MIMAT0003887 | MIRT039122 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040619 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040921 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041898 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046805 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
