HCSGD entry for DAZL


1. General information

Official gene symbolDAZL
Entrez ID1618
Gene full namedeleted in azoospermia-like
Other gene symbolsDAZH DAZL1 DAZLA SPGYLA
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000166Nucleotide bindingIEAmolecular_function
GO:0003676Nucleic acid bindingIEAmolecular_function
GO:0003723RNA bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0007275Multicellular organismal developmentIEAbiological_process
GO:0007281Germ cell developmentTASbiological_process
GO:0007283SpermatogenesisIEAbiological_process
GO:0008494Translation activator activityIDAmolecular_function
GO:0045948Positive regulation of translational initiationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.02191062270.97451850990.35505461251.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.5077458814
GSE13712_SHEARDown-0.0355541031
GSE13712_STATICUp0.0459707968
GSE19018Up0.2180405443
GSE19899_A1Up0.2162428850
GSE19899_A2Up0.3291947838
PubMed_21979375_A1Up1.4178633464
PubMed_21979375_A2Up0.5370539225
GSE35957Up0.2097732766
GSE36640Up0.1795489584
GSE54402Up1.9915809671
GSE9593Up0.1413069558
GSE43922Up0.2398347636
GSE24585Down-0.1359564241
GSE37065Up0.0259309244
GSE28863_A1Down-0.0850382742
GSE28863_A2Down-0.0575708509
GSE28863_A3Up0.2511517193
GSE28863_A4Down-0.0389802844
GSE48662Down-0.0848982435

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT016720MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

21204633In this study, therefore, we report, for the first time, the expression of Crd-bp/Imp1 and Dazl in BM-MSCs
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