HCSGD entry for CYP26A1
1. General information
| Official gene symbol | CYP26A1 |
|---|---|
| Entrez ID | 1592 |
| Gene full name | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| Other gene symbols | CP26 CYP26 P450RAI P450RAI1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001972 | Retinoic acid binding | IDA | molecular_function |
| GO:0005506 | Iron ion binding | IEA | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006766 | Vitamin metabolic process | TAS | biological_process |
| GO:0006805 | Xenobiotic metabolic process | TAS | biological_process |
| GO:0007417 | Central nervous system development | IEA | biological_process |
| GO:0008152 | Metabolic process | TAS | biological_process |
| GO:0008401 | Retinoic acid 4-hydroxylase activity | IDA | molecular_function |
| GO:0009952 | Anterior/posterior pattern specification | IEA | biological_process |
| GO:0014032 | Neural crest cell development | IEA | biological_process |
| GO:0019825 | Oxygen binding | TAS | molecular_function |
| GO:0020037 | Heme binding | NAS | molecular_function |
| GO:0034653 | Retinoic acid catabolic process | IDA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0048384 | Retinoic acid receptor signaling pathway | IEA | biological_process |
| GO:0048387 | Negative regulation of retinoic acid receptor signaling pathway | TAS | biological_process |
| GO:0071300 | Cellular response to retinoic acid | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2616703887 | 0.9000821245 | 0.9548629280 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0381207505 |
| GSE13712_SHEAR | Up | 0.0428976311 |
| GSE13712_STATIC | Down | -0.6861136911 |
| GSE19018 | Up | 0.0939430632 |
| GSE19899_A1 | Up | 0.0930356006 |
| GSE19899_A2 | Up | 0.3033067749 |
| PubMed_21979375_A1 | Up | 0.4582318410 |
| PubMed_21979375_A2 | Up | 0.1998733140 |
| GSE35957 | Up | 0.1993592317 |
| GSE36640 | Up | 0.0840552488 |
| GSE54402 | Up | 0.0309293417 |
| GSE9593 | Up | 0.0493126257 |
| GSE43922 | Up | 0.0109719825 |
| GSE24585 | Down | -0.1324699926 |
| GSE37065 | Down | -0.0834190183 |
| GSE28863_A1 | Up | 0.0047410376 |
| GSE28863_A2 | Up | 0.1646797810 |
| GSE28863_A3 | Up | 0.3615577120 |
| GSE28863_A4 | Up | 0.0371279831 |
| GSE48662 | Up | 0.2280342770 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018549 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-132-3p | MIMAT0000426 | MIRT021786 | Microarray | Functional MTI (Weak) | 17612493 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
