HCSGD entry for AK8
1. General information
| Official gene symbol | AK8 |
|---|---|
| Entrez ID | 158067 |
| Gene full name | adenylate kinase 8 |
| Other gene symbols | C9orf98 DDX31 RP11-143F18.1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004017 | Adenylate kinase activity | IDA | molecular_function |
| GO:0004127 | Cytidylate kinase activity | IDA | molecular_function |
| GO:0004550 | Nucleoside diphosphate kinase activity | IDA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005829 | Cytosol | IEA | cellular_component |
| GO:0006165 | Nucleoside diphosphate phosphorylation | IDA | biological_process |
| GO:0009142 | Nucleoside triphosphate biosynthetic process | IDA | biological_process |
| GO:0021591 | Ventricular system development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4087061890 | 0.8475203222 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0967617085 |
| GSE13712_SHEAR | Down | -0.1612722939 |
| GSE13712_STATIC | Down | -0.1780207339 |
| GSE19018 | Down | -0.0736504560 |
| GSE19899_A1 | Up | 0.0831451409 |
| GSE19899_A2 | Up | 0.1588176533 |
| PubMed_21979375_A1 | Up | 0.1687164732 |
| PubMed_21979375_A2 | Down | -0.0049877084 |
| GSE35957 | Up | 0.0111753977 |
| GSE36640 | Down | -0.0137601287 |
| GSE54402 | Down | -0.0690604300 |
| GSE9593 | Up | 0.0876048730 |
| GSE43922 | Up | 0.0185947520 |
| GSE24585 | Up | 0.6833261855 |
| GSE37065 | Down | -0.0231616210 |
| GSE28863_A1 | Up | 0.0243576626 |
| GSE28863_A2 | Down | -0.0533026710 |
| GSE28863_A3 | Up | 0.3031655881 |
| GSE28863_A4 | Up | 0.0054006854 |
| GSE48662 | Up | 0.4204681953 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Bis(Adenosine)-5'-Pentaphosphate | DB01717 | EXPT00535 |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
