HCSGD entry for CYP4B1

1. General information

Official gene symbolCYP4B1
Entrez ID1580
Gene full namecytochrome P450, family 4, subfamily B, polypeptide 1
Other gene symbolsCYPIVB1 P-450HP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004497Monooxygenase activityIEAmolecular_function
GO:0005506Iron ion bindingIEAmolecular_function
GO:0005789Endoplasmic reticulum membraneTAScellular_component
GO:0006805Xenobiotic metabolic processTASbiological_process
GO:0008144Drug bindingIEAmolecular_function
GO:0016705Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygenIEAmolecular_function
GO:0018585Fluorene oxygenase activityIEAmolecular_function
GO:0018879Biphenyl metabolic processIEAbiological_process
GO:0018917Fluorene metabolic processIEAbiological_process
GO:0019825Oxygen bindingTASmolecular_function
GO:0020037Heme bindingIEAmolecular_function
GO:0042738Exogenous drug catabolic processIEAbiological_process
GO:0043231Intracellular membrane-bounded organelleIEAcellular_component
GO:0044281Small molecule metabolic processTASbiological_process
GO:0070330Aromatase activityIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.66051551230.92262290570.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0121810887
GSE13712_SHEARUp0.0447160015
GSE13712_STATICUp0.1193232859
GSE19018Down-0.0760669127
GSE19899_A1Up0.0060914259
GSE19899_A2Up0.0608149539
PubMed_21979375_A1Up0.1104050859
PubMed_21979375_A2Up0.0371021101
GSE35957Up0.1787520927
GSE36640Down-0.0289860405
GSE54402Down-0.0111814014
GSE9593Up0.1337888762
GSE43922Up0.0406293832
GSE24585Down-0.0101070625
GSE37065Down-0.0115609426
GSE28863_A1Up0.0386558643
GSE28863_A2Up0.1107831020
GSE28863_A3Up0.1828865547
GSE28863_A4Up0.0001155820
GSE48662Up0.0040047047

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.