HCSGD entry for ESCO2
1. General information
| Official gene symbol | ESCO2 |
|---|---|
| Entrez ID | 157570 |
| Gene full name | establishment of sister chromatid cohesion N-acetyltransferase 2 |
| Other gene symbols | 2410004I17Rik EFO2 RBS |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0000785 | Chromatin | IDA IEA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0006275 | Regulation of DNA replication | IEA IMP | biological_process |
| GO:0007062 | Sister chromatid cohesion | IEA | biological_process |
| GO:0016746 | Transferase activity, transferring acyl groups | IEA | molecular_function |
| GO:0034421 | Post-translational protein acetylation | IEA IMP | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9464546788 | 0.0023693021 | 0.9999902473 | 0.0946318665 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2309364239 |
| GSE13712_SHEAR | Down | -0.1169118047 |
| GSE13712_STATIC | Up | 0.0320885163 |
| GSE19018 | Down | -0.0199387394 |
| GSE19899_A1 | Down | -0.0649803967 |
| GSE19899_A2 | Down | -1.0996359065 |
| PubMed_21979375_A1 | Down | -0.4383525495 |
| PubMed_21979375_A2 | Down | -0.5251061571 |
| GSE35957 | Down | -0.2307766825 |
| GSE36640 | Down | -1.9614881451 |
| GSE54402 | Down | -0.1158652458 |
| GSE9593 | Down | -0.2117612727 |
| GSE43922 | Down | -2.7191324694 |
| GSE24585 | Up | 0.0635774020 |
| GSE37065 | Down | -1.0708712822 |
| GSE28863_A1 | Down | -0.4793698505 |
| GSE28863_A2 | Up | 1.4587701504 |
| GSE28863_A3 | Down | -0.5763472936 |
| GSE28863_A4 | Down | -0.0349437317 |
| GSE48662 | Down | -1.0354402286 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-128-3p | MIMAT0000424 | MIRT022088 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026818 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
