HCSGD entry for CYP2J2
1. General information
| Official gene symbol | CYP2J2 |
|---|---|
| Entrez ID | 1573 |
| Gene full name | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| Other gene symbols | CPJ2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005506 | Iron ion binding | IEA | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006690 | Icosanoid metabolic process | TAS | biological_process |
| GO:0006805 | Xenobiotic metabolic process | TAS | biological_process |
| GO:0008016 | Regulation of heart contraction | TAS | biological_process |
| GO:0008392 | Arachidonic acid epoxygenase activity | IDA | molecular_function |
| GO:0008404 | Arachidonic acid 14,15-epoxygenase activity | IDA | molecular_function |
| GO:0008405 | Arachidonic acid 11,12-epoxygenase activity | IDA | molecular_function |
| GO:0019369 | Arachidonic acid metabolic process | TAS | biological_process |
| GO:0019373 | Epoxygenase P450 pathway | IDA TAS | biological_process |
| GO:0020037 | Heme binding | IEA | molecular_function |
| GO:0043651 | Linoleic acid metabolic process | IDA | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0070330 | Aromatase activity | IEA | molecular_function |
| GO:0071614 | Linoleic acid epoxygenase activity | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4232651343 | 0.9063062308 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0190614249 |
| GSE13712_SHEAR | Down | -0.0119002005 |
| GSE13712_STATIC | Down | -0.3185424956 |
| GSE19018 | Up | 0.2775132823 |
| GSE19899_A1 | Up | 0.0812649249 |
| GSE19899_A2 | Up | 0.1753035150 |
| PubMed_21979375_A1 | Up | 0.1815434390 |
| PubMed_21979375_A2 | Down | -0.0092321621 |
| GSE35957 | Up | 0.1880459369 |
| GSE36640 | Up | 0.2039300658 |
| GSE54402 | Up | 0.0527385873 |
| GSE9593 | Up | 0.0839533636 |
| GSE43922 | Up | 0.0169878393 |
| GSE24585 | Up | 0.1423827409 |
| GSE37065 | Up | 0.3584463153 |
| GSE28863_A1 | Up | 0.0698005961 |
| GSE28863_A2 | Up | 0.0902492664 |
| GSE28863_A3 | Up | 0.1359456662 |
| GSE28863_A4 | Down | -0.0552451855 |
| GSE48662 | Down | -0.0773947618 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7b-5p | MIMAT0000063 | MIRT006875 | Luciferase reporter assay//qRT-PCR//Western blot | Functional MTI | 22761738 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
