HCSGD entry for CYP2F1
1. General information
| Official gene symbol | CYP2F1 |
|---|---|
| Entrez ID | 1572 |
| Gene full name | cytochrome P450, family 2, subfamily F, polypeptide 1 |
| Other gene symbols | C2F1 CYP2F |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004497 | Monooxygenase activity | IEA TAS | molecular_function |
| GO:0005506 | Iron ion binding | IEA | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006805 | Xenobiotic metabolic process | TAS | biological_process |
| GO:0009636 | Response to toxic substance | IEA | biological_process |
| GO:0016705 | Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | IEA | molecular_function |
| GO:0016712 | Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | IDA | molecular_function |
| GO:0018931 | Naphthalene metabolic process | IDA | biological_process |
| GO:0018979 | Trichloroethylene metabolic process | IEA | biological_process |
| GO:0019825 | Oxygen binding | IEA | molecular_function |
| GO:0020037 | Heme binding | IEA | molecular_function |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0070330 | Aromatase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3463679951 | 0.7807857756 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1298800066 |
| GSE13712_SHEAR | Up | 0.0781769397 |
| GSE13712_STATIC | Up | 0.1684779106 |
| GSE19018 | Up | 0.2139757017 |
| GSE19899_A1 | Up | 0.1236455765 |
| GSE19899_A2 | Down | -0.1584428162 |
| PubMed_21979375_A1 | Down | -0.0230769607 |
| PubMed_21979375_A2 | Down | -0.0079326671 |
| GSE35957 | Up | 0.0880211506 |
| GSE36640 | Down | -0.0863372841 |
| GSE54402 | Up | 0.0019024862 |
| GSE9593 | Down | -0.0218272901 |
| GSE43922 | Down | -0.0449205930 |
| GSE24585 | Up | 0.1036237248 |
| GSE37065 | Up | 0.0447865514 |
| GSE28863_A1 | Up | 0.0644695003 |
| GSE28863_A2 | Up | 0.0579160623 |
| GSE28863_A3 | Up | 0.5541223469 |
| GSE28863_A4 | Up | 0.0089495604 |
| GSE48662 | Down | -0.0512390041 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017971 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029482 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord

