HCSGD entry for CYP2C18


1. General information

Official gene symbolCYP2C18
Entrez ID1562
Gene full namecytochrome P450, family 2, subfamily C, polypeptide 18
Other gene symbolsCPCI CYP2C CYP2C17 P450-6B/29C P450IIC17
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004497Monooxygenase activityTASmolecular_function
GO:0005506Iron ion bindingIEAmolecular_function
GO:0005789Endoplasmic reticulum membraneTAScellular_component
GO:0006805Xenobiotic metabolic processTASbiological_process
GO:0019825Oxygen bindingTASmolecular_function
GO:0020037Heme bindingIEAmolecular_function
GO:0044281Small molecule metabolic processTASbiological_process
GO:0070330Aromatase activityIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.84472578170.84209040310.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0044200589
GSE13712_SHEARDown-0.1391706524
GSE13712_STATICDown-0.0550637704
GSE19018Up0.0275459499
GSE19899_A1Down-0.0004188211
GSE19899_A2Up0.0518126275
PubMed_21979375_A1Up0.1758980135
PubMed_21979375_A2Up0.0245573411
GSE35957Up0.1991313540
GSE36640Up0.0011659844
GSE54402Down-0.0607200033
GSE9593Down-0.0666807942
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.0487274791

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

4-METHYL-N-METHYL-N-(2-PHENYL-2H-PYRAZOL-3-YL)BENZENESULFONAMIDEDB07670 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.