HCSGD entry for ADRB3

1. General information

Official gene symbolADRB3
Entrez ID155
Gene full nameadrenoceptor beta 3
Other gene symbolsBETA3AR
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002024Diet induced thermogenesisIEAbiological_process
GO:0002025Vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressureIEAbiological_process
GO:0002032Desensitization of G-protein coupled receptor protein signaling pathway by arrestinIDAbiological_process
GO:0004939Beta-adrenergic receptor activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0005975Carbohydrate metabolic processTASbiological_process
GO:0006091Generation of precursor metabolites and energyTASbiological_process
GO:0006112Energy reserve metabolic processTASbiological_process
GO:0006898Receptor-mediated endocytosisIDAbiological_process
GO:0007187G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messengerTASbiological_process
GO:0007188Adenylate cyclase-modulating G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007189Adenylate cyclase-activating G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0007190Activation of adenylate cyclase activityIDAbiological_process
GO:0007568AgingIEAbiological_process
GO:0009409Response to coldIEAbiological_process
GO:0015052Beta3-adrenergic receptor activityIMPmolecular_function
GO:0031649Heat generationIEAbiological_process
GO:0031699Beta-3 adrenergic receptor bindingIEAmolecular_function
GO:0040015Negative regulation of multicellular organism growthIEAbiological_process
GO:0042755Eating behaviorIEAbiological_process
GO:0042803Protein homodimerization activityIDAmolecular_function
GO:0043235Receptor complexIDAcellular_component
GO:0043410Positive regulation of MAPK cascadeIDAbiological_process
GO:0046677Response to antibioticIEAbiological_process
GO:0050873Brown fat cell differentiationIEAbiological_process
GO:0051379Epinephrine bindingIEAmolecular_function
GO:0051380Norepinephrine bindingIDAmolecular_function
GO:0071875Adrenergic receptor signaling pathwayIDA IMPbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.76333908290.82885359980.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0786659254
GSE13712_SHEARUp0.0059657456
GSE13712_STATICUp0.1091810155
GSE19018Up0.0078080436
GSE19899_A1Down-0.0630787093
GSE19899_A2Up0.1236235277
PubMed_21979375_A1Up0.0368539565
PubMed_21979375_A2Up0.2774023341
GSE35957Up0.0994666838
GSE36640Up0.0093982355
GSE54402Up0.0443642284
GSE9593Down-0.0209675334
GSE43922Up0.0166854620
GSE24585Down-0.2390807159
GSE37065Down-0.0521291229
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.0222239878

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

PropranololDB00571 APRD00194
ArbutamineDB01102 APRD00802
EphedraDB01363 -
SR 58611DB05395 -
SolabegronDB06190 -
DroxidopaDB06262 -
BopindololDB08807 -
BupranololDB08808 -
MirabegronDB08893 -
BethanidineDB00217 APRD00825
OlanzapineDB00334 APRD00138
MephentermineDB01365 -
BufuralolDB06726 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.