HCSGD entry for RASGEF1B

1. General information

Official gene symbolRASGEF1B
Entrez ID153020
Gene full nameRasGEF domain family, member 1B
Other gene symbolsGPIG4
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005085Guanyl-nucleotide exchange factor activityIEAmolecular_function
GO:0005088Ras guanyl-nucleotide exchange factor activityIDAmolecular_function
GO:0005622IntracellularIEAcellular_component
GO:0005769Early endosomeIEAcellular_component
GO:0005770Late endosomeIEAcellular_component
GO:0007264Small GTPase mediated signal transductionIEAbiological_process
GO:0030496MidbodyIEAcellular_component
GO:0032318Regulation of Ras GTPase activityIDAbiological_process
GO:0043087Regulation of GTPase activityIDAbiological_process
GO:0051056Regulation of small GTPase mediated signal transductionIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.38228054790.91243959960.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0373170242
GSE13712_SHEARUp0.0628349327
GSE13712_STATICDown-0.0607004401
GSE19018Up0.0765947403
GSE19899_A1Up0.0990161878
GSE19899_A2Up0.0577074970
PubMed_21979375_A1Up0.0184924192
PubMed_21979375_A2Up0.1186962598
GSE35957Up0.0006978187
GSE36640Up0.0532434971
GSE54402Up0.0158494340
GSE9593Up0.0016473918
GSE43922Up0.0050151692
GSE24585Up0.3148912321
GSE37065Up0.7948292162
GSE28863_A1Down-0.0117523967
GSE28863_A2Up0.0454270361
GSE28863_A3Up0.1004904648
GSE28863_A4Up0.0390850754
GSE48662Up0.0386018278

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.