HCSGD entry for CYB5A
1. General information
| Official gene symbol | CYB5A |
|---|---|
| Entrez ID | 1528 |
| Gene full name | cytochrome b5 type A (microsomal) |
| Other gene symbols | CYB5 MCB5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004033 | Aldo-keto reductase (NADP) activity | TAS | molecular_function |
| GO:0004129 | Cytochrome-c oxidase activity | TAS | molecular_function |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005741 | Mitochondrial outer membrane | TAS | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0006766 | Vitamin metabolic process | TAS | biological_process |
| GO:0006767 | Water-soluble vitamin metabolic process | TAS | biological_process |
| GO:0006810 | Transport | TAS | biological_process |
| GO:0006812 | Cation transport | TAS | biological_process |
| GO:0015672 | Monovalent inorganic cation transport | TAS | biological_process |
| GO:0016020 | Membrane | IDA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0019852 | L-ascorbic acid metabolic process | TAS | biological_process |
| GO:0019899 | Enzyme binding | IPI | molecular_function |
| GO:0020037 | Heme binding | IEA | molecular_function |
| GO:0034220 | Ion transmembrane transport | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
| GO:1902600 | Hydrogen ion transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9036805744 | 0.0136401618 | 0.9999902473 | 0.2299335253 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2361041517 |
| GSE13712_SHEAR | Down | -0.2098616437 |
| GSE13712_STATIC | Down | -0.1227763023 |
| GSE19018 | Up | 0.4316544962 |
| GSE19899_A1 | Down | -1.1725153025 |
| GSE19899_A2 | Down | -0.7247440815 |
| PubMed_21979375_A1 | Down | -1.1213952408 |
| PubMed_21979375_A2 | Down | -0.4503055584 |
| GSE35957 | Up | 0.0090104949 |
| GSE36640 | Up | 0.4670795633 |
| GSE54402 | Down | -0.7963065562 |
| GSE9593 | Up | 0.0027570871 |
| GSE43922 | Down | -0.8902405649 |
| GSE24585 | Down | -0.2440280603 |
| GSE37065 | Down | -0.2612557848 |
| GSE28863_A1 | Up | 0.1388995435 |
| GSE28863_A2 | Up | 0.4186981388 |
| GSE28863_A3 | Down | -0.2841266359 |
| GSE28863_A4 | Up | 0.0551545308 |
| GSE48662 | Down | -0.3199102517 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Dimethyl Propionate Ester Heme | DB04009 | EXPT01714 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT023043 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
