HCSGD entry for CTSZ
1. General information
| Official gene symbol | CTSZ |
|---|---|
| Entrez ID | 1522 |
| Gene full name | cathepsin Z |
| Other gene symbols | CTSX |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002003 | Angiotensin maturation | TAS | biological_process |
| GO:0005615 | Extracellular space | IDA | cellular_component |
| GO:0005764 | Lysosome | IEA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0008234 | Cysteine-type peptidase activity | IEA | molecular_function |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0060441 | Epithelial tube branching involved in lung morphogenesis | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4139413320 | 0.2247877246 | 0.9999902473 | 0.9119355271 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1231132543 |
| GSE13712_SHEAR | Up | 0.2144704343 |
| GSE13712_STATIC | Up | 0.3289012224 |
| GSE19018 | Up | 0.1106861215 |
| GSE19899_A1 | Down | -0.4547920833 |
| GSE19899_A2 | Up | 0.3292746798 |
| PubMed_21979375_A1 | Up | 0.4640631711 |
| PubMed_21979375_A2 | Up | 0.5313336765 |
| GSE35957 | Down | -0.6532279079 |
| GSE36640 | Up | 1.1436980876 |
| GSE54402 | Down | -0.2640090797 |
| GSE9593 | Up | 0.2443850183 |
| GSE43922 | Down | -0.0222096187 |
| GSE24585 | Up | 0.0094116619 |
| GSE37065 | Down | -0.1806520504 |
| GSE28863_A1 | Down | -0.2994730127 |
| GSE28863_A2 | Down | -0.3230157179 |
| GSE28863_A3 | Down | -0.1609793994 |
| GSE28863_A4 | Up | 0.0262621995 |
| GSE48662 | Down | -0.1146512606 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-128-3p | MIMAT0000424 | MIRT021991 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029430 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039629 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-505-3p | MIMAT0002876 | MIRT041024 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
