HCSGD entry for SPICE1
1. General information
| Official gene symbol | SPICE1 |
|---|---|
| Entrez ID | 152185 |
| Gene full name | spindle and centriole associated protein 1 |
| Other gene symbols | CCDC52 SPICE |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005814 | Centriole | IDA | cellular_component |
| GO:0005819 | Spindle | IDA | cellular_component |
| GO:0046599 | Regulation of centriole replication | IMP | biological_process |
| GO:0051310 | Metaphase plate congression | IMP | biological_process |
| GO:0090307 | Spindle assembly involved in mitosis | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1215983891 | 0.3847757570 | 0.7128265479 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.5008350079 |
| GSE13712_SHEAR | Up | 0.0779402321 |
| GSE13712_STATIC | Up | 0.1893515132 |
| GSE19018 | Up | 0.4332615226 |
| GSE19899_A1 | Up | 0.2997345596 |
| GSE19899_A2 | Down | -0.1991443055 |
| PubMed_21979375_A1 | Up | 0.4595764489 |
| PubMed_21979375_A2 | Down | -0.0200393649 |
| GSE35957 | Down | -0.8972762924 |
| GSE36640 | Down | -0.4528569252 |
| GSE54402 | Up | 0.1666178389 |
| GSE9593 | Down | -0.3885419063 |
| GSE43922 | Up | 0.5026389896 |
| GSE24585 | Up | 0.7012156798 |
| GSE37065 | Up | 0.1345801966 |
| GSE28863_A1 | Up | 0.3621635575 |
| GSE28863_A2 | Up | 0.2919076169 |
| GSE28863_A3 | Down | -0.2301096815 |
| GSE28863_A4 | Down | -0.2624668282 |
| GSE48662 | Up | 0.0302983475 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-27a-3p | MIMAT0000084 | MIRT028713 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
