HCSGD entry for ADRA2B

1. General information

Official gene symbolADRA2B
Entrez ID151
Gene full nameadrenoceptor alpha 2B
Other gene symbolsADRA2L1 ADRA2RL1 ADRARL1 ALPHA2BAR alpha-2BAR
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000165MAPK cascadeIEAbiological_process
GO:0001525AngiogenesisIEAbiological_process
GO:0003056Regulation of vascular smooth muscle contractionIEAbiological_process
GO:0004938Alpha2-adrenergic receptor activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process
GO:0007267Cell-cell signalingTASbiological_process
GO:0007565Female pregnancyIEAbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0010700Negative regulation of norepinephrine secretionNAS TASbiological_process
GO:0030168Platelet activationTASbiological_process
GO:0032148Activation of protein kinase B activityIDAbiological_process
GO:0032811Negative regulation of epinephrine secretionNASbiological_process
GO:0035625Epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathwayIDAbiological_process
GO:0045666Positive regulation of neuron differentiationIDAbiological_process
GO:0045777Positive regulation of blood pressureIEAbiological_process
GO:0051379Epinephrine bindingIDAmolecular_function
GO:0070474Positive regulation of uterine smooth muscle contractionIEAbiological_process
GO:0071883Activation of MAPK activity by adrenergic receptor signaling pathwayIDAbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.56227592800.84429886400.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0521305448
GSE13712_SHEARDown-0.0022638631
GSE13712_STATICUp0.1103392144
GSE19018Up0.0633643019
GSE19899_A1Down-0.0353984933
GSE19899_A2Up0.0368563501
PubMed_21979375_A1Up0.3221217141
PubMed_21979375_A2Down-0.2229251469
GSE35957Up0.1192981965
GSE36640Down-0.0057463110
GSE54402Down-0.0387868726
GSE9593Up0.0306612407
GSE43922Up0.2389244237
GSE24585Up0.2187558342
GSE37065Down-0.0562111871
GSE28863_A1Down-0.1374396294
GSE28863_A2Down-0.0151760500
GSE28863_A3Up0.2225265039
GSE28863_A4Up0.0520774162
GSE48662Up0.0730883812

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.