HCSGD entry for SMYD1
1. General information
| Official gene symbol | SMYD1 |
|---|---|
| Entrez ID | 150572 |
| Gene full name | SET and MYND domain containing 1 |
| Other gene symbols | BOP KMT3D ZMYND18 ZMYND22 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003714 | Transcription corepressor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006338 | Chromatin remodeling | IEA | biological_process |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0007507 | Heart development | IEA | biological_process |
| GO:0010831 | Positive regulation of myotube differentiation | IDA | biological_process |
| GO:0018024 | Histone-lysine N-methyltransferase activity | IEA | molecular_function |
| GO:0035914 | Skeletal muscle cell differentiation | IEA | biological_process |
| GO:0045663 | Positive regulation of myoblast differentiation | IDA | biological_process |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4925590669 | 0.9290928194 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0319056731 |
| GSE13712_SHEAR | Down | -0.0320258302 |
| GSE13712_STATIC | Up | 0.0281885879 |
| GSE19018 | Up | 0.1167874334 |
| GSE19899_A1 | Up | 0.0772378105 |
| GSE19899_A2 | Up | 0.0813864199 |
| PubMed_21979375_A1 | Up | 0.2008384838 |
| PubMed_21979375_A2 | Down | -0.0286985867 |
| GSE35957 | Up | 0.2457123365 |
| GSE36640 | Up | 0.0014907837 |
| GSE54402 | Up | 0.0313286023 |
| GSE9593 | Down | -0.0195814629 |
| GSE43922 | Up | 0.0069805863 |
| GSE24585 | Down | -0.0376602440 |
| GSE37065 | Down | -0.0546947341 |
| GSE28863_A1 | Up | 0.0549347527 |
| GSE28863_A2 | Up | 0.1170388205 |
| GSE28863_A3 | Up | 0.3798147083 |
| GSE28863_A4 | Up | 0.0774735564 |
| GSE48662 | Up | 0.0397282047 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017526 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-151a-5p | MIMAT0004697 | MIRT038201 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-28-5p | MIMAT0000085 | MIRT050011 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
