HCSGD entry for AIFM3
1. General information
| Official gene symbol | AIFM3 |
|---|---|
| Entrez ID | 150209 |
| Gene full name | apoptosis-inducing factor, mitochondrion-associated, 3 |
| Other gene symbols | AIFL |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | IDA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0016491 | Oxidoreductase activity | IEA | molecular_function |
| GO:0045454 | Cell redox homeostasis | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0050660 | Flavin adenine dinucleotide binding | IEA | molecular_function |
| GO:0051537 | 2 iron, 2 sulfur cluster binding | IEA | molecular_function |
| GO:0097194 | Execution phase of apoptosis | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2310771855 | 0.5679811025 | 0.9146752556 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0564203567 |
| GSE13712_SHEAR | Down | -0.2173653061 |
| GSE13712_STATIC | Down | -0.1177652574 |
| GSE19018 | Down | -0.0161300480 |
| GSE19899_A1 | Down | -0.0712007925 |
| GSE19899_A2 | Up | 0.1340730599 |
| PubMed_21979375_A1 | Down | -0.0187301175 |
| PubMed_21979375_A2 | Up | 0.1823039546 |
| GSE35957 | Down | -0.1144407590 |
| GSE36640 | Down | -0.0574226971 |
| GSE54402 | Down | -0.1506347843 |
| GSE9593 | Down | -0.0379073938 |
| GSE43922 | Up | 0.0835136497 |
| GSE24585 | Up | 0.0840875441 |
| GSE37065 | Down | -0.0529544643 |
| GSE28863_A1 | Up | 0.1262152118 |
| GSE28863_A2 | Down | -0.2214236077 |
| GSE28863_A3 | Up | 1.2853518632 |
| GSE28863_A4 | Up | 0.1880070004 |
| GSE48662 | Up | 0.1135827774 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-210-3p | MIMAT0000267 | MIRT006326 | Luciferase reporter assay | Functional MTI | 22387901 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
