HCSGD entry for AANAT

1. General information

Official gene symbolAANAT
Entrez ID15
Gene full namearalkylamine N-acetyltransferase
Other gene symbolsDSPS SNAT
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004059Aralkylamine N-acetyltransferase activityIDA IEA NASmolecular_function
GO:0004060Arylamine N-acetyltransferase activityIEAmolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006474N-terminal protein amino acid acetylationIDAbiological_process
GO:0007623Circadian rhythmIEA IMP NASbiological_process
GO:0009416Response to light stimulusIEAbiological_process
GO:0010043Response to zinc ionIEAbiological_process
GO:0030187Melatonin biosynthetic processIDA IEA NASbiological_process
GO:0032868Response to insulinIEAbiological_process
GO:0034097Response to cytokineIEAbiological_process
GO:0034641Cellular nitrogen compound metabolic processTASbiological_process
GO:0034695Response to prostaglandin EIEAbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046219Indolalkylamine biosynthetic processTASbiological_process
GO:0046688Response to copper ionIEAbiological_process
GO:0048471Perinuclear region of cytoplasmIDAcellular_component
GO:0051412Response to corticosteroneIEAbiological_process
GO:0051591Response to cAMPIEAbiological_process
GO:0051592Response to calcium ionIEAbiological_process
GO:0071320Cellular response to cAMPIDAbiological_process
GO:007188914-3-3 protein bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.35911277310.89819514460.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1059338830
GSE13712_SHEARDown-0.0763959981
GSE13712_STATICUp0.2342217288
GSE19018Down-0.1180014019
GSE19899_A1Up0.0768430138
GSE19899_A2Down-0.0068580918
PubMed_21979375_A1Down-0.2341167356
PubMed_21979375_A2Up0.0462689964
GSE35957Up0.0087948709
GSE36640Up0.3252639371
GSE54402Up0.0873283565
GSE9593Up0.0251134305
GSE43922Up0.2144408653
GSE24585Up0.1546615865
GSE37065Up0.0940091343
GSE28863_A1Down-0.0975366938
GSE28863_A2Down-0.1147247087
GSE28863_A3Up0.4340879437
GSE28863_A4Up0.0889437153
GSE48662Up0.1210024668

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Coa-S-Trimethylene-Acetyl-TryptamineDB01777 EXPT00818
Coa-S-Acetyl TryptamineDB02931 EXPT00990
Coa-S-Acetyl 5-BromotryptamineDB03341 EXPT00819

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.