HCSGD entry for EXOC8


1. General information

Official gene symbolEXOC8
Entrez ID149371
Gene full nameexocyst complex component 8
Other gene symbolsEXO84 Exo84p SEC84
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000145ExocystIEAcellular_component
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006887ExocytosisIEAbiological_process
GO:0015031Protein transportIEAbiological_process
GO:0030426Growth coneIEAcellular_component
GO:0034613Cellular protein localizationIEAbiological_process
GO:0044267Cellular protein metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.05462998370.92623820140.51026110721.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1203998497
GSE13712_SHEARUp0.1912998693
GSE13712_STATICUp0.3047386639
GSE19018Down-0.3605126747
GSE19899_A1Up0.4732140018
GSE19899_A2Up0.3311620706
PubMed_21979375_A1Up0.8567442778
PubMed_21979375_A2Up0.4861596561
GSE35957Up0.2985553777
GSE36640Up0.4574096019
GSE54402Up0.1299998957
GSE9593Up0.2739044404
GSE43922Up0.1335584894
GSE24585Down-0.0736148697
GSE37065Up0.0783621732
GSE28863_A1Up0.3361529677
GSE28863_A2Up0.4335547296
GSE28863_A3Down-0.2087837384
GSE28863_A4Down-0.3051170393
GSE48662Up0.0153720893

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-21-5pMIMAT0000076MIRT030740MicroarrayFunctional MTI (Weak)18591254
hsa-miR-1226-3pMIMAT0005577MIRT036462CLASHFunctional MTI (Weak)23622248
hsa-miR-615-3pMIMAT0003283MIRT039884CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.