HCSGD entry for CSTF3
1. General information
| Official gene symbol | CSTF3 |
|---|---|
| Entrez ID | 1479 |
| Gene full name | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| Other gene symbols | CSTF-77 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000398 | MRNA splicing, via spliceosome | TAS | biological_process |
| GO:0003723 | RNA binding | TAS | molecular_function |
| GO:0005634 | Nucleus | IDA IEA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006369 | Termination of RNA polymerase II transcription | TAS | biological_process |
| GO:0006378 | MRNA polyadenylation | TAS | biological_process |
| GO:0006379 | MRNA cleavage | TAS | biological_process |
| GO:0006396 | RNA processing | IEA | biological_process |
| GO:0008380 | RNA splicing | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0031124 | MRNA 3'-end processing | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0226630827 | 0.9466446070 | 0.3597535865 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.6337131014 |
| GSE13712_SHEAR | Up | 0.1653181621 |
| GSE13712_STATIC | Up | 0.1992358829 |
| GSE19018 | Down | -0.0061890345 |
| GSE19899_A1 | Up | 0.3520023145 |
| GSE19899_A2 | Up | 0.4727287760 |
| PubMed_21979375_A1 | Up | 0.5576692969 |
| PubMed_21979375_A2 | Up | 0.0960805097 |
| GSE35957 | Down | -0.8720031714 |
| GSE36640 | Down | -0.0642477406 |
| GSE54402 | Up | 0.1096593777 |
| GSE9593 | Down | -0.5498609524 |
| GSE43922 | Up | 0.3883264457 |
| GSE24585 | Up | 0.0699448355 |
| GSE37065 | Up | 0.0224634700 |
| GSE28863_A1 | Up | 0.7259928213 |
| GSE28863_A2 | Up | 0.4306798863 |
| GSE28863_A3 | Up | 0.0369524897 |
| GSE28863_A4 | Up | 0.3031248613 |
| GSE48662 | Up | 0.0062919229 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022875 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-1 | MIMAT0000416 | MIRT023876 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-24-3p | MIMAT0000080 | MIRT030582 | Microarray | Functional MTI (Weak) | 19748357 |
| hsa-miR-378a-3p | MIMAT0000732 | MIRT043935 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-132-3p | MIMAT0000426 | MIRT045842 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
